Ovarian Stromal and Germ Cell Tumors

Clinical and Pathologic Features of Patients with Rare Ovarian Tumors: Multi-Center Review of 167 Patients by the Anatolian Society of Medical Oncology

“…They have different biological behaviors with a variety of histopathological subtypes; in addition, they have curative potential with different treatment approaches compared with much more commonly encountered epithelian ovarian cancers (Quirk and Natarajan, 2005;Young, 2005;Ayhan et al, 2009;Koulouris and Penson, 2009;Colombo et al, 2012;Penson, 2013;Takeuchi et al, 2013). The cure rates of early stage GCTs approach 100%, and even in the advanced stage of the disease, surgery and the BEP regimen result in cure rates of approximately 75% (Gershenson, 2007;Parkinson et al, 2011;Matei et al, 2013).…”

“…In ROTs, the clarification of prognostic factors that have an impact on survival is important for accurate diagnosis and treatment strategies, such as surgery, adjuvant treatment, and effective treatment of relapse (Garcia et al, 1999;Koulouris and Penson, 2009;Colombo et al, 2012). Because these tumors are rarely encountered in clinical practice, randomized clinical trials to evaluate the effects of proposed treatment regimens are limited in the literature.…”

Hormonaktive Ovarialtumoren

“…Granulosazelltumoren (GZT) sind mit einem Anteil von etwa 70-90% die mit Abstand häufigsten Keimstrangtumoren [2,7,13]. Risikofaktoren für das Auftreten eines GZT scheinen Adipositas sowie eine positive Familienanamnese für Mammaund Ovarialkarzinom zu sein.…”

Laparoscopic Management of Early-Stage Malignant Nonepithelial Ovarian Tumors

“…1 Malignant nonepithelial ovarian tumors are mainly composed of sex cordYstromal tumors and germ cell tumors that generally present unilaterally at early stages and have a relatively good prognosis. 2 In addition, MNEOTs are more frequent among young women than epithelial ovarian malignancies. 1 Particularly, in the first 2 decades of life, approximately 70% of ovarian tumors are of germ cell origin, and one third of these are malignant.…”