Ovarian sex cord stromal tumor with annular tubules in a 7-year-old child: A case report

Abstract

HighlightSex cord stromal tumor with annular tubules has low malignant potential with late recurrence.Oophorectomy is the main stay of treatment.Long term follow-up is important.

Non-Peutz–Jeghers syndrome-associated ovarian sex cord tumor with annular tubules treated by radiotherapy: a case report and literature review

“…Furthermore, the radiotherapy details, such as total dose, effectiveness, and adverse events remain unknown. [1][2][3][4]9,13 Our patient developed recurrence twice, and with metastasis to multiple sites, namely as a large mediastinal mass, and masses in the right pericardium, bilateral hilum, and left adrenal region. After surgery and adjuvant chemotherapy, some of the metastatic tumors decreased in size, but the patient's serum estrogen and progesterone concentrations remained high.…”

“…Furthermore, the radiotherapy details, such as total dose, effectiveness, and adverse events remain unknown. 1 – 4 , 9 , 13 …”

“…Peutz–Jeghers syndrome (PJS), a hereditary cancer syndrome characterized by mucocutaneous melanin pigmentation and gastrointestinal polyposis, has been well-acknowledged as an important cause in the pathogenesis of SCTAT. 2 For example, approximately 1/3 of SCTAT patients are reported to present with PJS.…”

Non-syndromic bilateral ovarian sex cord stromal tumor with annular tubules in a postmenopausal elderly woman as an incidental finding

“…Ca-125 was increased in 3 patients: the highest (211 U/mL) was reported in a 34-year-old patient with a 12 cm unilateral tumor after her second recurrence; our current case with a bilateral SCTAT greater than 8 cm and Ca-125 level of 66.5 U/mL; and finally, a 14-year-old patient with a unilateral tumor of 27 cm and a result of 42.6 U/ ml (being the latter the only one who underwent the serum marker neuron specific enolase reported as 84.29 H G/M). No abnormalities were found in other serum tumor markers including: AFP (0/12), CA 19-9 (0/10), CEA (0/10), B-HCG (0/5), CA242 (0/2), CA153 (0/2), CA724 (0/1), LDH (0/1) [ [6] , [7] , [8] , [9] , [10] , [11] , [12] ].…”