Ovarian response to the human chorionic gonadotrophin stimulation test in normal ovulatory women: the impact of regressing corpus luteum

Järvelä, Ilkka Y.; Niinimäki, Maarit; Martikainen, Hannu; Ruokonen, Aimo; Tapanainen, Juha S.

doi:10.1016/j.fertnstert.2006.08.114

Cited by 12 publications

(7 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The vascularized volume of the dominant ovary correlated with serum progesterone and 17‐OHP levels before mifepristone administration. This finding is well in line with previous studies showing that circulating progesterone concentrations depend on the amount of steroidogenic tissue and blood flow in the corpus luteum23, 24. Vascularization in the corpus luteum remained unchanged after mifepristone administration, which suggests that the mechanism by which mifepristone affects progesterone production is not associated with the changes in ovarian vasculature.…”

Section: Discussionsupporting

confidence: 92%

Effect of mifepristone on the corpus luteum in early pregnancy

Niinimäki

Ruokonen

Tapanainen

et al. 2009

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

Effect of mifepristone on the corpus luteum in early pregnancy

Niinimäki

Ruokonen

Tapanainen

et al. 2009

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

show abstract

“…In patients who became pregnant, the 17-OHP and E 2 levels increased, most probably reflecting the rescue of the corpus luteum by hCG secreted from the trophoblastic tissue [20]. On the contrary, in patients who failed, the dominant ovarian volume decreased by the second set of measurements and 17-OHP levels were lower than in pregnant women, reflecting the continuing regression of the corpus luteum without hCG stimulation.…”

Section: Discussionmentioning

confidence: 99%

Assessment of endometrial and ovarian characteristics using three dimensional power Doppler ultrasound to predict response in frozen embryo transfer cycles

Žáčková

Järvelä

Tapanainen

et al. 2009

Reprod Biol Endocrinol

View full text Add to dashboard Cite

ObjectiveTo evaluate whether endometrial or ovarian parameters as measured using 3D power Doppler ultrasound would predict the outcome in frozen embryo transfer (FET) cycles.MethodsThirty women with no known gynecological pathology undergoing FET were recruited. The FET was carried out in the natural menstrual cycle 3-4 days after the first positive LH test result. Blood samples for hormonal analysis were collected, and three-dimensional (3D) ultrasonographic examination was performed on the day of the FET and repeated with analysis of the total hCG one week later.ResultsThe demographic, clinical, and embryological characteristics were similar between the pregnant (15/30) and nonpregnant groups (15/30). There were no differences between the groups in endometrial/subendometrial thickness, volume, or vascularization index (VI). The endometrial triple-line pattern was more often present in the pregnant group on the day of the FET (93.3% vs. 40.0%, 95% CI 25.5-81.2%). No differences in the ovaries were observed on the day of the FET. At the second visit, the triple-line pattern was still more often present in those patients who had conceived (91.7% vs. 42.9%, 95% CI 18.5-79.1%), and their corpus luteum was more active as judged by the rise in 17-hydroxyprogesterone and estradiol levels. No differences were observed in the dominant ovarian vasculature.ConclusionsAccording to our results, measurement of power Doppler indices using 3D ultrasound on the day of the FET does not provide any additional information concerning the outcome of the cycle. The existence of the triple-line pattern on the day of the FET seems to be a prognostic sign of a prosperous outcome after FET. The dominant ovary in the pregnant group seems to be already activated one week after the FET.

show abstract

“…The details of ultrasonographic examination including volume acquisition, storage, and analysis have been described in detail elsewhere . We used 3‐D ultrasonography (Voluson Expert 730; Kretz, Zipf, Austria) equipped with a transvaginal probe to examine the ovaries and the uterus.…”

Section: Methodsmentioning

confidence: 99%

“…A computer‐aided analysis imaging program (VOCAL, GE Healthcare, Zipf, Austria) for 3‐D power Doppler histogram analysis was used to determine the volume and vascularization in the ovary containing the corpus luteum. The manual mode of the VOCAL Contour Editor was used to cover the entire 3‐D volume of the ovary, with 30° rotation steps . Hence, six contour planes were analysed for each ovary to cover 180°.…”

Section: Methodsmentioning

confidence: 99%