Ovarian Reserve After Surgical Treatment of Unilateral Benign Ovarian Cyst

Said, Tamer H.; Sibai, F. El; Rocca, M.; Kholif, Ahmed E.; Ahmed, A.I.; Soliman, Ashraf T; Magarelli, P.C.

doi:10.1016/j.fertnstert.2009.01.045

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Said et al . [ 14 ] concluded removal of endometriotic cysts with the stripping technique is associated with direct trauma to the ovarian cortex with destruction of the follicles. In a study by Ercan et al .,[ 4 ] on the 2 nd day after surgery a significant increase in the ovarian volume was detected on the operated ovary, which may be the result of edema due stripping procedure.…”

Section: Commentsmentioning

confidence: 99%

Laparoscopic cystectomy of endometrioma: Good surgical technique does not adversely affect ovarian reserve

Bhat¹,

Dhulked²,

Ramachandran³

et al. 2014

J Hum Reprod Sci

View full text Add to dashboard Cite

BACKGROUND:The damage to ovarian reserve inflicted by surgery for endometriosis represents a major concern in the balance between reproductive benefits and risks.AIM:To evaluate the ovarian reserve in sub fertile women after laparoscopic endometriotic cystectomy.SETTINGS AND DESIGN:Prospective study, done in Department of Obstetrics and Gynecology, tertiary care hospital between August 2010-2012.MATERIALS AND METHOD:Laparoscopic cystectomy performed by stripping technique for endometriotic cysts. Endometriosis was staged according to revised American Society of Reproductive Medicine classification (rASRM). Ovarian reserve assessed by comparing FSH and LH levels, measurement of residual ovarian volume, antral follicle counts and stromal blood flow on second day of menses pre and postoperatively. Cyst wall was evaluated histologically to note the presence of normal ovarian tissue in resected tissue.STATISTICAL ANALYSIS:SPSS for Windows version 16.0 (SPSS Inc., Chicago, IL) was used for statistical calculations. Wilcoxon signed test and Pearson Chi – Square test were applied. Significance level was P < 0.05.RESULTS:Incidence of minimal, mild, moderate, and severe endometriosis was 4.1%, 21.9%, 28.7%, 45.3% respectively. Ovarian reserve was assessed both by ultrasound and biochemical parameters on day 2 of menses; pre and post-operatively. Preoperative and post-operative values; FSH (7.24 ± 1.21, 7.23 ± 1.51 m IU/ml), LH levels (6.37 ± 1.8, 6.6 ± 2.3 m IU/ml), residual ovarian volume (8.5 cm3 ± 5.3, 7.4 cm3 ± 5.8), antral follicle count(3.3 ± 1.9, 4.1 ± 1.5) and stromal blood flow (6.8 cm/sec ± 4.57, 7.1 cm/sec ± 3.55) were statistically not significant. Loss of follicle was seen in 27.2% cyst walls on histopathological examination while 72.73% had no loss.CONCLUSION:Laparoscopic cystectomy when performed for endometriotic cysts with accurate surgical technique leads to no significant ovarian tissue removal.

show abstract

Section: Commentsmentioning

confidence: 99%

Laparoscopic cystectomy of endometrioma: Good surgical technique does not adversely affect ovarian reserve

Bhat¹,

Dhulked²,

Ramachandran³

et al. 2014

J Hum Reprod Sci

View full text Add to dashboard Cite

show abstract

“…The study showed a statistically significant decline in surgical trauma in a three-step procedure compared with cystectomy alone. 14 Said et al 15 evaluated ovarian reserve following surgical treatment of unilateral ovarian cyst and concluded that stripping technique of removal of cysts is associated with direct trauma to the remaining ovarian cortex with wall analysis; however, the observation was not found to be statistically significant.…”

Section: Resultsmentioning

confidence: 99%

Size of Endometrioma and Number does Influence the Ovarian Reserve: A Prospective Observational Study

Sandya¹,

Kumar

2016

International Journal of Infertility &Amp; Fetal Medicine

View full text Add to dashboard Cite

Background Endometriosis is one of the most commonly encountered benign problems in gynecology. Ultrasound and endocrine parameters have been widely accepted as markers of ovarian reserve. Anti-Mullerian hormone (AMH) in conjugation with antral follicle counts is now believed to be an excellent measure for detecting ovarian reserve. Surgical approach has a fundamental role in the management of endometriosis. The loss of normal follicles can be studied by histopathological assessment of the cyst wall. The postoperative decline in the ovarian reserve is believed to have a correlation with number of endometriomas and diameter of the cyst wall. Objective This prospective observational study was undertaken to evaluate the effect of laparoscopic cystectomy with respect to number and size of the cyst on ovarian reserve parameters. Materials and methods Fifty patients undergoing laparoscopic endometrioma cystectomy were analyzed. Cysts of <5cm and >5cm and the number of cysts were studied. Statistical analysis was done using Mauchly's test of sphericity. Anti-Mullerian hormone and antral follicle count were estimated prior to and 1 month after surgery. Pre- and postoperative values were compared and analyzed with respect to number and size of endometrioma. Observation and results There was an overall drop of AMH from 3.8 ± 3.01 to 2.67 ± 1.92 ng/ml (p < 0.001). The mean AMH in bilateral and unilateral endometrioma was 2.9 ± 1.7 and 3.9 ± 3.17 ng/ml respectively. Anti-Mullerian hormone dropped from 4.53 ± 3.4 to 3.19 ± 2.18 with <5 cm cyst compared with 2.4 ± 1.2 to 1.7 ± 0.85 with >5 cm cyst (p < 0.01). Overall drop in AFC was 5.17 ± 1.44 and 3.61 ± 1.61 pre- and postoperative respectively (p < 0.01). Mean drop in AFC was 2.2 and 1.2 in cyst <5 and > 5 cm respectively. Histopathological analysis showed loss of follicles in 25% of the cyst walls. This was correlating with the drop in both AMH and AFC postoperatively. Conclusion Size and number of cyst does affect ovarian reserve to the effect that smaller and bilateral cyst leads to a greater decline in the same. How to cite this article Sandya MR, Kumar P. Size of Endometrioma and Number does Influence the Ovarian Reserve: A Prospective Observational Study. Int J Infertil Fetal Med 2016;7(1):14-18.

show abstract

“…Said et al, (29) concluded that removal of endometriotic growths with stripping had been related to direct injury to the ovarian cortex with destruction of the follicles.…”

Section: Histopathological Evaluationmentioning

confidence: 99%

Impact of Laparoscopic Ovarian Cystectomy Versus Laparoscopic Coagulation on Ovarian Reserve in Cases of Ovarian Endometrioma

Shalal

El-Sayed

Mahdy

et al. 2017

Zagazig University Medical Journal

View full text Add to dashboard Cite

show abstract

Ovarian Reserve After Surgical Treatment of Unilateral Benign Ovarian Cyst

Cited by 3 publications

References 0 publications

Laparoscopic cystectomy of endometrioma: Good surgical technique does not adversely affect ovarian reserve

Laparoscopic cystectomy of endometrioma: Good surgical technique does not adversely affect ovarian reserve

Size of Endometrioma and Number does Influence the Ovarian Reserve: A Prospective Observational Study

Impact of Laparoscopic Ovarian Cystectomy Versus Laparoscopic Coagulation on Ovarian Reserve in Cases of Ovarian Endometrioma

Contact Info

Product

Resources

About