Ovarian Metastasis Is Associated with Retroperitoneal Lymph Node Relapses in Women Treated for Colorectal Peritoneal Carcinomatosis

Abstract

Retroperitoneal lymph node recurrence seems to be linked to OM originating from colorectal cancer and could worsen the prognosis. A systematic lymphadenectomy could be evaluated in women with isolated OM or very limited peritoneal carcinomatosis to analyze the incidence of invaded lymph nodes and study its potential benefit on survival.

Impact of ovarian metastases on survival in patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancy originating from appendiceal and colorectal cancer

“…Two previous studies have investigated the outcomes of CRS and HIPEC in patients with, and without, ovarian metastases, although in both studies the majority, or all, of the study population had colorectal peritoneal metastases [24,25]. In addition, the study population of 405 patients in the current study exceeds that of the other studies (105 and 125 patients, respectively).…”

“…The extent of peritoneal disease was graded using the peritoneal cancer index (PCI), which ranges from 0 to 39 [13]. The median PCI was 18 (interquartile range, IQR, [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26]. Median follow-up was 40 months (IQR 27-59).…”

The role of surgical excision for the Krukenberg tumour: A case report

“…Cytoreductive surgery (CRS) for KTs carries a significant locoregional or metastatic recurrence rate despite achieving an initial R0 resection. KTs in particular have been linked to retroperitoneal lymph node recurrence [8] . It has been suggested that should KT be discovered incidentally upon resection of a colorectal primary, systematic second-look surgery should be performed to exclude peritoneal metastasis [9] .…”

Conversion therapy of gastric cancer with massive malignant ascites and ovarian metastases by systemic and intraperitoneal chemotherapy

“…Peng et al reported that gastrectomy and absence of ascites were the two independent prognostic factors associated with longer survival in gastric cancer (16). In addition, for colorectal cancer with peritoneal metastases, the presence of ovarian metastases did not affect prognosis in patients undergoing complete cytoreductive surgery with IP chemotherapy (17). Removing microscopic residual tumor is the expected effect of the surgery.…”