Ovarian hyperstimulation syndrome management strategies: where are we going?

Eskew, Ashley M.; Omurtag, Kenan

doi:10.23736/s0391-1977.17.02638-4

Cited by 8 publications

(2 citation statements)

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“…The size of both ovaries is usually normal before pregnancy or during the conception cycle, and the ovaries are polycystic after natural conception. 21,22 Our patient mainly complained about abdominal tension. We also found peritoneal and pelvic ascites, decreased albumin levels, and increased CA-125 levels.…”

Section: Discussionmentioning

confidence: 93%

Spontaneous ovarian hyperstimulation syndrome in a nonpregnant female patient: a case report and literature review

Chai

et al. 2020

J Int Med Res

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Spontaneous ovarian hyperstimulation syndrome (sOHSS) usually occurs in patients with a spontaneous ovulation cycle, especially in those with multiple pregnancies combined with hypothyroidism and polycystic ovary syndrome. sOHSS rarely occurs in women who are not pregnant. A 23-year-old woman with obvious abdominal distension visited our hospital. The patient was not pregnant and had not undergone controlled superovulation. Apart from abdominal distension, the patient denied any symptom of obvious incentives, abdominal pain, abnormal vaginal bleeding, or drainage. Biochemical analysis showed a high carbohydrate antigen-125 level and low total protein and albumin levels. Abdominal ultrasound and computed tomography showed a large amount of ascites and cystic uneven masses with an irregular shape in the area of the ovaries and fallopian tubes. Post-surgical histopathology indicated the diagnosis of sOHSS. Wedge resection of both ovaries was performed. Symptomatic treatment was further performed and the patient recovered well. Our findings indicate that sOHSS can occur in women who are not pregnant. Additionally, besides the follicle-stimulating hormone receptor gene mutation hypothesis, the pathogenesis of sOHSS should be further studied.

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Section: Discussionmentioning

confidence: 93%

Spontaneous ovarian hyperstimulation syndrome in a nonpregnant female patient: a case report and literature review

Chai

et al. 2020

J Int Med Res

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“…The symptoms of iatrogenic OHSS consist of abdominal pain, distension, nausea, vomiting, pleural effusion, hemoconcentration, ascites, and systemic edema ( 19 , 23 ). It is noteworthy that the patient did not present any of the systemic conditions attributed to OHSS.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous ovarian hyperstimulation syndrome in a pregnant woman with hypothyroidism: a case report

et al. 2021

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Objective To study a rare case of spontaneous ovarian hyperstimulation syndrome in a naturally conceived pregnancy associated with overt hypothyroidism. Design Case report. Setting Endocrinology private practice. Patient(s) A 32-year-old woman who was 13 weeks pregnant with bilaterally enlarged ovaries presumed to be secondary to hypothyroidism. Intervention(s) Administration of levothyroxine and titration of the dose. Main Outcome Measure(s) Regression of signs and symptoms of spontaneous ovarian hyperstimulation syndrome after 12 weeks of therapy. Result(s) The patient was diagnosed with severe hypothyroidism, as confirmed by her elevated thyroid-stimulating hormone level. Ultrasound evaluation revealed ovarian enlargement secondary to multiple contiguous cysts with anechoic content. The patient was administered levothyroxine 175 μg/day. Results of hormonal studies demonstrated thyroid function normality at week 12 after treatment. Incomplete regression of ovarian cysts was also noticed within this period. At week 37, the patient developed preeclampsia, and cesarean delivery was recommended. An 8-month postpartum ultrasound evaluation revealed complete regression of the cysts. Conclusion(s) Spontaneous ovarian hyperstimulation syndrome secondary to hypothyroidism may be the cause of ovarian enlargement, and levothyroxine replacement seems an appropriate primary therapeutic option. Proper endocrinological assessment of patients is recommended as it may avoid unfavorable outcomes.

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Ovarian Hyperstimulation: Pathophysiology, Risk Factors, Prevention, and Management

Tserotas

Neyro

2021

Obstetric Catastrophes

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Ovarian hyperstimulation syndrome management strategies: where are we going?

Cited by 8 publications

References 0 publications

Spontaneous ovarian hyperstimulation syndrome in a nonpregnant female patient: a case report and literature review

Spontaneous ovarian hyperstimulation syndrome in a nonpregnant female patient: a case report and literature review

Spontaneous ovarian hyperstimulation syndrome in a pregnant woman with hypothyroidism: a case report

Ovarian Hyperstimulation: Pathophysiology, Risk Factors, Prevention, and Management

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