Ovarian Function After Hysterectomy With Conservation of the Ovaries in Pre‐menopausal Women

Beavis, E. L. G.; Brown, J. B.; Smith, Margery A.

doi:10.1111/j.1471-0528.1969.tb09462.x

Cited by 74 publications

(27 citation statements)

References 30 publications

(10 reference statements)

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“…If the diseased ovaries were precancerous, those women who might otherwise have developed ovarian cancer do not. Following hysterectomy with ovarian conservation, reduced ovarian function or ovarian failure occurs in a proportion of women, due possibly to the blood supply to the ovaries being compromised (Beavis et al, 1969;Ellsworth et al, 1983). Female sterilisation was also associated with a low risk of ovarian cancer.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for ovarian cancer: a case-control study

Booth

Beral²,

Smith³

1989

Br J Cancer

282

238

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(2), benign neoplasms of the digestive organs (4) respiratory system (4) and other sites (8) and various other conditions and symptoms (94). This final category included patients with haemorrhoids (15) and those with symptoms relating to the respiratory system (10), gastrointestinal tract (20) and urinary system (10).Maximum likelihood estimates of relative risk (RR) together with their 95% confidence interval (95% CI) and tests for trend where appropriate were computed by multiple logistic regression techniques (Breslow & Day, 1980) using the GLIM statistical package (Baker & Nelder, 1978). All relative risks have been adjusted for age in 5-year strata (20-24, 25-29, . . . 60-64)

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Section: Discussionmentioning

confidence: 99%

Risk factors for ovarian cancer: a case-control study

Booth

Beral²,

Smith³

1989

Br J Cancer

282

238

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“…Serum androgen levels decline steeply in the early reproductive years but do not vary as a consequence of natural menopause and, for many postmenopausal women, the ovary seems to continue to be an ongoing site of testosterone production. [21][22][23][24][25][26] Importantly, testosterone stimulates bone and muscle formation and even small amounts of circulating testosterone seem to have a beneficial protective effect on bone loss and fracture risk. [27][28][29][30][31][32] …”

Section: Hormonal Differences Between Natural Menopause and Surgical mentioning

confidence: 99%

Surgical Menopause

Rodríguez

Shoupe

2015

Endocrinology and Metabolism Clinics of North America

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In addition to the common symptoms that occur after natural menopause, special considerations apply to women who have had their ovaries removed, particularly when oophorectomy occurs before age 45 years. Women with premenopausal oophorectomy have more severe and prolonged menopausal symptoms. Their risks of adverse mood, heart disease, excessive bone resorption, sexual dysfunction, and cognitive disorders are increased compared with the general population. Retention of the ovaries carries a survival benefit for women at low risk of ovarian malignancy. Women facing oophorectomy should understand the balance of risks and benefits in order to make an informed decision.

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“…In this report, four of the seven post-hysterectomy women, whose MR images suggested active ovarian function, actually showed physiological FDG uptake in the ovaries. The phenomenon was expected because many investigators have reported that women of the reproductive age and whose ovaries are preserved showed normal ovarian function with a cyclic change of pituitary gonadotropins and ovarian hormones or ovulatory cycles after hysterectomy [11][12][13][14].…”

Section: Discussionmentioning

confidence: 99%