Ovarian endometriosis: a form of genital endometriosis or a specific nosological unit

Davydov, A.I.; Mikhaleva, L.M.; Tairova, M.B.; Patsap, Olga I.

doi:10.20953/1726-1678-2019-5-5-12

Cited by 2 publications

(2 citation statements)

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“… 18 The clear-cell and endometrioid carcinomas are the most common malignancies in such cases. 19 …”

Section: Resultsmentioning

confidence: 99%

“…18 The clear-cell and endometrioid carcinomas are the most common malignancies in such cases. 19 Notably, some animals who do not have menstrual cycles do not suffer from endometriosis. 20 Only menstruating primate females suffer from endometriosis, which evolves spontaneously, thereby suggesting the etiopathogenetic association of this disease with uterine specificity and mechanisms involved in menstruation.…”

Section: Endometriosis Development Theorymentioning

confidence: 99%

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Current Knowledge on Endometriosis Etiology: A Systematic Review of Literature

Михалева¹,

Radzinsky²,

Оразов³

et al. 2021

IJWH

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Objective To review the mechanisms of endometriosis development, including those related to epigenetic mutations, cellular dysregulation, inflammatory processes, and oxidative stress. Methods A systematic literature review regarding current aspects of endometriosis etiology, genesis and development was performed using the PubMed, Google Scholar, and eLibrary databases. Keywords included endometriosis, etiology, development, genesis, associations and mechanisms. A multilingual search was performed. Results Several mechanisms underline the pathophysiological pathways for endometriosis development. Epigenetic mutations, external and internal influences, and chronic conditions have a significant impact on endometriosis development, survival and regulation. Several historically valid theories on endometriosis development were discussed, as well as updated findings. Conclusion Despite recent advances, fundamental problems in understanding endometriosis remain unresolved. The identification of unknown circulating epithelial progenitors or stem cells that are responsible for epithelial growth in both the endometrium and endometriotic foci seems to be the next step in solving these questions.

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“… 18 The clear-cell and endometrioid carcinomas are the most common malignancies in such cases. 19 …”

Section: Resultsmentioning

confidence: 99%

Section: Endometriosis Development Theorymentioning

confidence: 99%