Outcomes of thoracoscopic clipping versus transcatheter occlusion of patent ductus arteriosus: Randomized clinical trial

Treatment Options for Pediatric Patent Ductus Arteriosus

“…Eight studies met the inclusion criteria and were included in the analysis (one RCT and seven observational cohort studies), for a total of 1,107 children ( Fig 1 ). [15][16][17][18][19][20][21][22] Study characteristics are summarized in Table 1 . We identified one RCT performed at a single center in Vietnam.…”

“…We identified one RCT performed at a single center in Vietnam. 22 In this study, 100 patients were randomized equally to either VATS surgical ligation or catheter-based treatment with either the Amplatzer occluder or fl ipper coils based on PDA size. In the seven observational cohort studies, 1,007 children were treated for PDA.…”

“…In the RCT, no patients in the surgical arm required reintervention, compared with three patients in the catheter-based treatment arm. 22 Complications were defi ned as any clinically important complication directly related to the procedure itself. Examples for the surgery group included recurrent laryngeal nerve injury, need for chest tube (chylothorax, pneumothorax, or other), and diaphragmatic paralysis.…”

“…In the RCT, no complications were seen in either treatment group. 22 Of the observational studies, six reported LOS. 15,16,[18][19][20][21] As with the RCT, in the observational studies, surgical patients had a longer LOS ( Table 3 ).…”

Coarctation of the Aorta as a Complication of Surgical Ligation of Patent Ductus Arteriosus in a Premature Infant

“…A large meta-analysis showed that both surgical and transcatheter approaches for PDA closure have comparable outcomes. Reintervention is more common with catheter-based interventions, but overall complication rates are similar and hospital stay is significantly shorter [6]. …”