Outcomes of Infant Cardiac Surgery for Congenital Heart Disease Concomitant With Persistent Pneumonia: A Retrospective Cohort Study

Luo, Hui; Qin, Gang; Wang, Lu; Liu, Yang; Pan, Yundan; Huang, Lei; Luo, Wanjun; Guo, Qulian; Peng, Yonggang; Wang, E.

doi:10.1053/j.jvca.2018.05.039

Cited by 5 publications

(2 citation statements)

References 12 publications

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“…CHD patients in LMICs are considered to have a very different spectrum of disease (2,5,6,18,19). These patients present late and majority of the time have associated co-morbidities like infections, severe malnourishment, and significant lung injury (especially in shunt lesions) due to repeated pneumonia (20)(21)(22)(23)(24)(25). These patients thus have different physiological states than similar patients presenting in HIR (i.e., advanced pulmonary vascular obstructive disease, significantly elevated filling pressures due to prolonged volume load etc.)…”

Section: Discussionmentioning

confidence: 99%

Performance of a Risk Analytic Tool (Index of Tissue Oxygen Delivery “IDO2”) in Pediatric Cardiac Intensive Care Unit of a Developing Country

et al. 2022

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ObjectiveTo determine the performance of a commercially available risk analytic tool (IDO2) to estimate the risk for SVO2 < 40% in patients admitted in cardiac intensive care unit (CICU).MethodsMedical and T3 records of all patients (aged 1 day to 12 years, weight >2 kg) who received care in the CICU between October 1st, 2019 and October 1st, 2020, had SvO2 lab(s) drawn during CICU course and whose data was transmitted to T3, were included. The average IDO2 Index was computed in the 30-min period immediately prior to each SvO2 measurement and used as a predictor score for SvO2 < 40%.ResultsA total of 69 CICU admissions from 65 patients, median age 9.3 months (interquartile range 20.8) were identified. Surgical and medical patients were 61 (88%) and 8 (12%) respectively; 4 (5.7%) patients had single ventricle physiology. Tetralogy of Fallot n = 23 (33.3%) and ventricular septal defects 17 (24.6%) were major cardiac diagnosis. Sixty-one (89.9%) of the admissions were successfully discharged from the hospital. Of the 187-total included SvO2 labs, 17 (9%) were <40%. The AUC of estimating SvO2 < 40% IDO2 was 0.87 [confidence interval (CI): 0.79–0.94]. Average IDO2 above 75 had the highest absolute risk (42.11, CI: 20.25–66.50) and highest RR (4.63, CI: 2.31–9.28, p-value < 0.0001) of SvO2 < 40%.ConclusionIDO2 performed well in estimating low SvO2 (<40%) in pediatric patients presenting to a CICU in a low resource setting. Future work is needed to determine the effect of this risk analytic tool on clinical outcomes in such a setting.

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Section: Discussionmentioning

confidence: 99%

Performance of a Risk Analytic Tool (Index of Tissue Oxygen Delivery “IDO2”) in Pediatric Cardiac Intensive Care Unit of a Developing Country

et al. 2022

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“…The perioperative antibiotic prevention strategies we adopted were as follows: cefmetazole was given intravenously 30min before the operation, and another dose was given if the operation time was longer than three hours, and one dose was given within 24 hours after the operation according to the prescription formula. The diagnosis of postoperative pneumonia was mainly based on manifestations of fever, wheezing, cough, shortness of breath, wet rales auscultated on chest examination, and radiographic abnormalities such as spotty or patchy infiltration in a chest radiograph (17). Bacterial culture of airway secretions was helpful to identify pathogens and assist treatment.…”

Section: Study Design and Definitionmentioning

confidence: 99%

Effects of different oral care strategies on postoperative pneumonia in infants with mechanical ventilation after cardiac surgery: a prospective randomized controlled study

Huang

et al. 2021

Transl Pediatr

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Background: To explore the effects of different oral care strategies on postoperative pneumonia in infants with mechanical ventilation after cardiac surgery.Methods: A prospective randomized controlled study was conducted at a hospital in Fujian Province, China. Participants were randomly divided into the breast milk oral care group, physiological saline oral care group, and sodium bicarbonate oral care group to explore the effects of different oral care strategies on postoperative pneumonia in infants on mechanical ventilation cardiac surgery. Results:The mechanical ventilation duration, the hospitalization costs, and the length of intensive care unit (ICU) stay and postoperative hospital stay in the breast milk oral care group were significantly shorter than those in the physiological saline oral care group and the sodium bicarbonate oral care group. The incidence of postoperative pneumonia in the breast milk oral care group was 3.2%, which was significantly lower than that in the physiological saline oral care group (22.6%) and the sodium bicarbonate oral care group (19.4%).Conclusions: Using breast milk for oral care in infants after cardiac surgery has a lower incidence of postoperative pneumonia than traditional oral care strategies of physiological saline and sodium bicarbonate, and it is worthy of clinical application.

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Bayesian Inference and Dynamic Neural Feedback Promote the Clinical Application of Intelligent Congenital Heart Disease Diagnosis

Tan

Cao

et al. 2023

Engineering

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Outcomes of Infant Cardiac Surgery for Congenital Heart Disease Concomitant With Persistent Pneumonia: A Retrospective Cohort Study

Cited by 5 publications

References 12 publications

Performance of a Risk Analytic Tool (Index of Tissue Oxygen Delivery “IDO2”) in Pediatric Cardiac Intensive Care Unit of a Developing Country

Performance of a Risk Analytic Tool (Index of Tissue Oxygen Delivery “IDO2”) in Pediatric Cardiac Intensive Care Unit of a Developing Country

Effects of different oral care strategies on postoperative pneumonia in infants with mechanical ventilation after cardiac surgery: a prospective randomized controlled study

Bayesian Inference and Dynamic Neural Feedback Promote the Clinical Application of Intelligent Congenital Heart Disease Diagnosis

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