Outcomes of Boston Keratoprosthesis in Aniridia: A Retrospective Multicenter Study

Akpek, Esen K.; Harissi‐Dagher, Mona; Petrarca, Robert; Butrus, Salim I.; Pineda, Roberto; Aquavella, James V.; Dohlman, Claes H.

doi:10.1016/j.ajo.2007.04.036

Cited by 122 publications

(76 citation statements)

References 11 publications

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“…The common adverse denominator was clearly the degree of preoperative chronic inflammation. Subsequent outcome studies for subgroups followed for: Herpes simplex keratitis [48], Herpes zoster [63], aniridia [1], epithelial downgrowth into the anterior chamber [73], etc.-all showed quite good retention [22]. It is clearly in this general category of relatively low degree of inflammation that the B-KPro does the most good, with a side table before being sutured back into the patient's eye [5].…”

Section: Prognostic Categoriesmentioning

confidence: 96%

The Boston keratoprosthesis 2014: a step in the evolution of artificial corneas

Dohlman

Cruzat

White

2014

Spektrum Augenheilkd.

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Section: Prognostic Categoriesmentioning

confidence: 96%

The Boston keratoprosthesis 2014: a step in the evolution of artificial corneas

Dohlman

Cruzat

White

2014

Spektrum Augenheilkd.

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“…Glaucoma has been reported to occur in between 58-72% of patients who have received a Boston keratoprosthesis. [77][78][79] In one series of patients with aniridia, 14 of 15 (93%) patients had pre-existing glaucoma. Glaucoma surgery was performed in 4 of 15 (27%) patients before to implantation of the keratoprosthesis.…”

Section: Trabeculectomymentioning

confidence: 99%

Management of patients with combined glaucoma and corneal transplant surgery

Banitt

Lee

2009

Eye

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Penetrating keratoplasty (PKP) is associated with an increased risk of secondary glaucoma. The development of glaucoma after PKP is an important risk factor for decreased corneal graft survival. The incidence of glaucoma after corneal transplant as well as the mechanism of developing increased intraocular pressure is reviewed in this paper. Treatments for post-PKP glaucoma include medications, laser, and surgery. The most frequent surgical glaucoma intervention is implantation of a glaucomadrainage device. Recent advances in corneal transplantation surgery may help to decrease corneal failure and the risk of developing post-keratoplasty glaucoma.

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“…General indications are corneal allograft rejection, corneal vascularization, opacity with limbal stem cell deficiency (aniridia and others) and chemical burns [2,8,9]. Modified Kpro design, routine use of soft contact lens after surgery and long-term use of antibiotics have significantly reduced complication rates, leading to improved final visual outcomes with this procedure [10].…”

Section: Introductionmentioning

confidence: 99%

Influence of Primary Diagnosis and Complications on Visual Outcome in Patients Receiving a Boston Type 1 Keratoprosthesis

Nascimento

Paz²,

Rosandic³

et al. 2014

Ophthalmic Res

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Purpose: To analyse how primary diagnosis and complications affect the evolution of post-operative visual acuity (VA). Methods: We performed retrospective chart analysis on 59 eyes in 57 patients with various diagnoses, most of which were non-standard indications for Boston type 1 keratoprosthesis (Kpro) implantation. The follow-up period was at least 3 months. Patients were classified based on the evolution of post-operative VA: group A demonstrated stable VA improvement, group B lost VA improvement and group C no significant VA improvement. Results: We assigned 46% of our cases to group A with stable VA improvement, 32% to group B with lost VA improvement, and 22% to group C with no VA improvement. The number of graft failures before Kpro implantation did not influence VA outcome. Except for the relatively good VA outcome in chemical burn and radiation injury patients, there seems to be no association between primary diagnosis and positive or negative VA outcome. Only 9% of patients with posterior segment complications and 20% with infections and associated pathologies were assigned to group A. Conclusion: Most cases (78%) showed improvement in VA after Boston type 1 Kpro (groups A and B). Posterior segment complications and infections mostly resulted in persistent loss of vision. These complications should be prevented and carefully treated.

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Outcomes of Boston Keratoprosthesis in Aniridia: A Retrospective Multicenter Study

Cited by 122 publications

References 11 publications

The Boston keratoprosthesis 2014: a step in the evolution of artificial corneas

The Boston keratoprosthesis 2014: a step in the evolution of artificial corneas

Management of patients with combined glaucoma and corneal transplant surgery

Influence of Primary Diagnosis and Complications on Visual Outcome in Patients Receiving a Boston Type 1 Keratoprosthesis

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