Outcomes and Side effects of Duplex-Guided Sclerotherapy in the Treatment of Great Saphenous Veins with 1% versus 3% Polidocanol Foam: Results of a Randomized Controlled Trial with 1-Year Follow-Up

Abstract

In the treatment of primary incompetent greater saphenous veins, 3% polidocanol foam seems to be more effective than 1% polidocanol foam. The side effects were approximately similar in both groups.

Duplex Guided Foam Sclerotherapy Versus Surgery in Management of Primary Varicose Veins

“…This is somewhat higher than what has been reported in our study. Jia et al [37] showed pain and pigmentations were the two most important complications in foam group which is in accordance with the literature, pain in 4 (16%) patients and pigmentation 5 (20%) patients [51,52].…”

“…The 2% frequency of thromboembolic events in our subjects corresponds to reported thromboembolic event rates between 0.02% and 1.25% [52,53].…”

Abordagens cirúrgicas no tratamento de varizes

“…Em todos os ensaios a concentração de esclerosante foi de 3%. Um estudo que envolveu um total de 80 doentes e que compara a eficá-cia e efeitos laterais da escleroterapia com espuma a 1 vs. 3% conclui que com uma concentração mais elevada o procedimento parece ser mais eficaz, sendo os efeitos adversos equiparáveis 36 . Portanto, o facto de não ter sido avaliado nenhum ensaio em que fosse utilizado o esclerosante a 1% à partida não altera as conclusões gerais desta revisão.…”

Minimally invasive techniques in the treatment of saphenous varicose veins

“…For truncal varicosities, a 3% polidocanol foam appears to be more effective than 1% polidocanol foam but may cause more adverse events, such as hyperpigmentation and phlebitis. 16 After injection, patients remain horizontally or in reverse Trendelenburg position to enhance contact for 5 minutes or more. After therapy, cotton wool or foam pads can be applied over the tract of the veins and compression therapy (bandages, antithromboembolism stockings, and/or medical elastic compression stockings class II) are recommended for a period of 1 to 6 weeks.…”