In cardiovascular risks, OPG serum level might increase as a preventive compensatory mechanism to neutralize the RANKL level increment. The determination of the OPG-RANKL system is a diagnostic indicator for the intensity of vascular calcification and atherosclerosis in SSc patients.

Backgroundː Varicose veins is a major problem among adult population. It has a major effect on life quality as well as healthcare system resources, we aim in this study to compare ultrasound guided foam sclerotherapy (UGFS) with surgery in management of primary varicose veins patients and to measure patients' satisfaction with either modalities.

Background: Infragenicular angioplasty could salvage most of limbs under amputation impendence. We aim in our study to detect the results of infragenicular angioplasty in diabetic and non-diabetic patients with critical lower limb ischemia (CLI).

Aim: To compare the outcomes of infrapopliteal angioplasty between diabetic and non-diabetic patients with critical limb ischemia.Methods: From September 2014 to April 2015, infrapopliteal angioplasty was performed on 80 patients (43 men; mean age 70.13 years) with critical limb ischemia CLI (Fontaine`s grade III or IV). The number of diabetic patients was 40 (50%). Follow-up included clinical examination for rest pain improvement and ischemic ulcer healing, and duplex-documented target vessel patency or re-stenosis at discharge and at 3 months. Results:The technical success rate was 100% in diabetic and non diabetic groups. The ulcer healing rate was 33/37(89.18%) in diabetic patients vs. 28/30(93.3%) in non diabetic patients and the re-stenosis and re-occlusion rates of treated vessels after 3 months were 10.0% in diabetic vs. 5.0% in non diabetic groups. Conclusion:There were no significant differences between the 2 groups in the technical success rate, but the 3 months clinical success rate and the primary patency rate were better in non diabetic than in diabetic patients with significant differences.Recent hemorrhagic stroke or any other CNS abnormality with increased risk of hemorrhage.

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