Outcome with peritoneal dialysis compared to haemodialysis

Maiorca, R; Cancarini, Giovanni

doi:10.1007/978-94-017-3225-3_25

Cited by 6 publications

(8 citation statements)

References 120 publications

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“…This may predispose to the development of such complications of dialysis as hypertension, heart failure, and athero-/arteriosclerosis. Secondly, patients in our study did not suffer from severe liver diseases or cancer, as reported in adult studies [7]. However, one might hypothesize that infectious complications were almost eliminated by aggressive management.…”

Section: Discussionmentioning

confidence: 51%

“…This is slightly different from data presented by NAPRTCS, where both cardiovascular complications and infections were the main causes of death [4,5]. Adult studies show that, although cardiovascular complications were the main cause of death, they accounted for only about 50% of deaths [7]. The high incidence of cardiovascular complications may be related to a longer time on the waiting list for transplantation.…”

Section: Discussionmentioning

confidence: 57%

“…There were no statistically significant differences in survival between the two groups, but the total number of patients dialyzed for an adequate time was limited and this might limit the power of the statistical analysis. In last few years, some reports comparing survival in HD patients and CAPD/APD patients have been published [7]. In adult studies the mortality rate among CAPD/APD patients has increased after 2-3 years of PD.…”

Section: Discussionmentioning

confidence: 99%

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Patient survival and causes of death on hemodialysis and peritoneal dialysis - single-center study

Litwin¹,

Grenda²,

Prokurat³

et al. 2001

Pediatric Nephrology

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Survival and causes of death in children dialyzed in a single center were analyzed. During the last 12 years a chronic dialysis program was introduced in 146 children in our center and 125 of them, eligible for observation, were included in this analysis; 58 patients were on hemodialysis (HD) and 67 on peritoneal dialysis [continuous ambulatory peritoneal dialysis/automated peritoneal dialysis (CAPD/APD)]. Mean age at the start of dialysis was 13.1 years in HD and 9.8 years in CAPD/APD patients. Overall, 16 patients died (12.5%); 6 (10.3%) on HD and 10 (14.9%) on CAPD/APD; 4 HD patients died of hemorrhagic stroke and 2 were killed in road traffic accidents. Of 10 CAPD/APD patients, 7 died of heart failure, ischemic stroke, and/or disseminated thromboembolic disease. Another was killed in a road traffic accident and 2 died during the course of severe infections. The 1-year patient survival rate was 96.6% in HD patients and 95% in CAPD/APD patients, 2-year survival 94% and 93% and 5-year survival 91% and 78%, respectively (P=0.2, NS). In conclusion, the survival rate for HD and CAPD patients is similar, although after 2 years of therapy, it is lower in CAPD patients. The main causes of death are cardiovascular. However, in CAPD/APD patients, heart failure with low cardiac output and thromboembolic complications are major causes of death, and in HD patients the main cause is hemorrhagic stroke.

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Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%

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Patient survival and causes of death on hemodialysis and peritoneal dialysis - single-center study

Litwin¹,

Grenda²,

Prokurat³

et al. 2001

Pediatric Nephrology

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“…For the first 20 yr after the introduction of continuous ambulatory PD, numerous single-center and regional studies attempted to compare the outcomes in PD and MHD (26). Although the results of these studies were variable, the emerging consensus seemed to be that the outcomes with both of the modalities were similar; however, a study from the US Renal Data System raised questions about this assumption: In that analysis of comparative outcomes of prevalent MHD and PD patients with 170,700 patient-years of follow-up, the death rate for PD patients was 19% higher than that for MHD patients (27).…”

Section: Comparative Survival Data Between Mhd and Pdmentioning

confidence: 99%

Is the Declining Use of Long-Term Peritoneal Dialysis Justified by Outcome Data?

Khawar

Kalantar-Zadeh

et al. 2007

Clinical Journal of the American Society of Nephrology

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In the past decade, peritoneal dialysis use among patients with end-stage renal disease has declined in many countries. Studies from the United States indicate that many academic centers do not have adequate resources to train fellows, most incident dialysis patients are not offered peritoneal dialysis, and more than half of dialysis clinics do not have the infrastructure to support peritoneal dialysis. Some are concerned that the outcomes of peritoneal dialysis and maintenance hemodialysis patients may not be equivalent, a notion that is not supported by outcome studies. Given the effect of modality selection on patients' lifestyle, attempts to conduct a randomized, controlled comparison of maintenance hemodialysis and peritoneal dialysis have been unsuccessful. Most observational studies showed that peritoneal dialysis is associated with a survival advantage that diminishes over time; it is unclear whether any of the differences over time are attributable to the modality. Between 1996 and 2003, the early outcomes of peritoneal dialysis patients further improved, whereas those for maintenance hemodialysis patients remained unchanged. Differences in outcomes may be due to residual statistical confounding; however, several biologic mechanisms can be postulated: The early survival advantage may be related to the better preservation of residual renal function with peritoneal dialysis, and the diminution of the survival advantage may be related to worsened volume control. There is a need for large observational and interventional studies among peritoneal dialysis patients to sustain and enforce the improvements in both dialysis therapies.

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“…In recent years many studies have compared the clinical results of hemodialysis (HD) and chronic peritoneal dialysis (CPD) in adult patients [5,6], but very few reports on the pediatric experience are available [3,7,8,9]. In particular, data concerning long-term survival of children on HD and PD are scarce, and refer to single pediatric dialysis center experiences [10,11], or report an overall survival of patients on chronic dialysis [3].…”

Section: Introductionmentioning

confidence: 97%

A multicenter experience on patient and technique survival in children on chronic dialysis

Verrina

Edefonti

Gianoglio

et al. 2004

Pediatric Nephrology

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Outcome with peritoneal dialysis compared to haemodialysis

Cited by 6 publications

References 120 publications

Patient survival and causes of death on hemodialysis and peritoneal dialysis - single-center study

Patient survival and causes of death on hemodialysis and peritoneal dialysis - single-center study

Is the Declining Use of Long-Term Peritoneal Dialysis Justified by Outcome Data?

A multicenter experience on patient and technique survival in children on chronic dialysis

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