A multicenter experience on patient and technique survival in children on chronic dialysis

Verrina, Enrico; Edefonti, Alberto; Gianoglio, Bruno; Rinaldi, Stefano; Sorino, Palma; Zacchello, Graziella; Lavoratti, Giancarlo; Maringhini, Silvio; Pecoraro, Carmine; Calevo, Maria Grazia; Dertenois, Laura; Perfumo, Francesco

doi:10.1007/s00467-003-1270-6

Cited by 83 publications

(75 citation statements)

References 27 publications

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“…CAPD is the most commonly used PD modality at FUNDANIER and has a lower cost compared to APD [11]. CAPD modality at FUNDANIER had a higher reported peritonitis rate than APD, which is similar to what has been shown in other studies [22].…”

Section: Discussionsupporting

confidence: 83%

“…Peritonitis is the primary cause of catheter loss and withdrawal from dialysis treatment [10]. Peritonitis also presents a mortality risk of at least 1% and is the leading cause of death in children and adults on chronic PD [8,11,12]. It also presents a risk in low income countries where infection is more prevalent due to lower socioeconomic status and housing levels [7].…”

Section: Introductionmentioning

confidence: 99%

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Risk Factors for Peritonitis in a Pediatric Dialysis Program in Guatemala, 2011–2014

Chinchilla¹,

Sebastián²,

Meléndez

et al. 2016

Advances in Nephrology

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Background. Peritonitis is the most common complication of peritoneal dialysis but there is limited data regarding peritonitis related risk factors in developing countries. Objective. Describe the PD program at Foundation for Children with Kidney Disease (FUNDANIER), in Guatemala, and identify peritonitis related risk factors in these patients. Methods. This retrospective open cohort study included medical records from FUNDANIER during 2011 to 2014. Baseline demographics, treatment modalities, caregivers' characteristics, and socioeconomic status were recorded. Results. Eighty-nine medical records were included with a treatment time of 1855 months. Median age of patients was 11.3 years (range 6-17). Median duration of PD therapy was 20.8 months (range 1-28). Sixty-eight peritonitis episodes were registered; forty-eight patients (54%) remained peritonitis-free. Median time to first peritonitis episode was 5 months (range 2-16). Peritonitis rate was one episode every 27 months or 0.44 episodes per patient-year. Peritonitis rate in patients with fair housing was 2.5 times higher than in those with good housing (CI = 1.0-5.2, = 0.01). Conclusion. Housing conditions are a relevant risk factor related to peritonitis. Strategies toward preventing peritonitis must consider housing status, establishing adequate follow-up in high-risk patients. Close monitoring of technique serves to overcome understaffing issues in this setting.

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Section: Discussionsupporting

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Risk Factors for Peritonitis in a Pediatric Dialysis Program in Guatemala, 2011–2014

Chinchilla¹,

Sebastián²,

Meléndez

et al. 2016

Advances in Nephrology

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“…End-stage renal disease (ESRD) occurs rarely among children ,1 year of age, but for these children its consequences are profound. [1][2][3][4][5] Even with the early initiation of maintenance dialysis therapy, these patients are at high risk for a variety of morbidities and mortality. [6][7][8] This is especially true for those who initiate dialysis during the neonatal period.…”

Section: What This Study Addsmentioning

confidence: 99%

Outcome of Patients Initiating Chronic Peritoneal Dialysis During the First Year of Life

2015

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“…4) [62]. Peritoneal membrane failure is responsible for up to 27 % of PD termination [286,134]. The frequency of PD termination due to UF failure increases with the time of treatment, from 14 % in the first 5 years to 33 % thereafter [134].…”

Section: Treatment Outcome Long-term Preservation Of Peritoneal Membrmentioning

confidence: 98%

“…Despite a series of improvements in connection technology, peritonitis remains the single most common complications in PD children and the most important cause of morbidity hospitalization and technique failure [201,67,286]. Peritonitis annualized rate varies in different parts of the world, from 0.64 in North America [201] and 0.60 in Italy [139] to the exceptional rate of 0.17 episodes per PD treatment year in Japanese children [136].…”

Section: Infectious Complications Of Pd Peritonitismentioning

confidence: 99%

Peritoneal Dialysis in Children

Patel

Kv³

et al. 2015

Pediatric Nephrology

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In children with chronic kidney disease stage 5D peritoneal dialysis (PD) remains the dialysis modality most commonly prescribed, especially as automated PD. Nowadays it can be started from the first days of life on, and applied even to some preterm babies. This chapter gives an overview on PD membrane ultrastructure and function, on technical prerequistes of PD, on optimal PD prescription and on specific treatment targets and tools to monitor efficacy. It describes PD related infectious and noninfectious complications, long term peritoneal and systemic sequelae and current state of the art of how these can be mitigated or even be prevented.

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A multicenter experience on patient and technique survival in children on chronic dialysis

Abstract: In this study we compared patient and technique survival of 163 new hemodialysis (HD) patients (age 11.4€3.

Cited by 83 publications

References 27 publications

Risk Factors for Peritonitis in a Pediatric Dialysis Program in Guatemala, 2011–2014

Risk Factors for Peritonitis in a Pediatric Dialysis Program in Guatemala, 2011–2014

Outcome of Patients Initiating Chronic Peritoneal Dialysis During the First Year of Life

Peritoneal Dialysis in Children

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