Outcome of Very-Low-Birth-Weight Infants at 1 and 2 Yearse of Age

Kohlhauser, Christina; Fuiko, Renate; Panagl, Agnes; Zadra, C.; Haschke, N.; Brandstetter, Sophia; Weninger, M.; Pollak, Arnold

doi:10.1177/000992280003900801

Cited by 19 publications

(10 citation statements)

References 22 publications

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“…3,7,8,10,[32][33][34][35] Also, the brain maturation of preterm infants (especially the cerebellum) proceeds in a different way than in term infants. 3,4,10,29,30,32,36 Impaired growth of the cerebellum appears to be underestimated in preterm infants, although long-term neurodevelopmental disabilities may be in part attributable to this phenomenon.…”

Section: Discussionmentioning

confidence: 99%

Early gross motor development of preterm infants according to the Alberta Infant Motor Scale

Haastert

Vries

Helders

et al. 2006

The Journal of Pediatrics

167

103

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Section: Discussionmentioning

confidence: 99%

Early gross motor development of preterm infants according to the Alberta Infant Motor Scale

Haastert

Vries

Helders

et al. 2006

The Journal of Pediatrics

167

103

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“…However, an inaccurate diagnosis is common before toddler age, with misdiagnoses of cerebral palsy highest before 24 months. [6][7][8] Presently, identification of potential gross motor impairment in toddler-aged children is primarily based on clinical exam and motor milestone history. However, such assessments can yield poor specificity; in one study, half of the diagnoses of cerebral palsy made by the first birthday were retracted before the seventh.…”

Section: Introductionmentioning

confidence: 99%

Toddle temporal-spatial deviation index: Assessment of pediatric gait

Cahill‐Rowley

Rose

2016

Gait & Posture

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This research aims to develop a gait index for use in the pediatric clinic as well as research, that quantifies gait deviation in 18-22 month-old children: the Toddle Temporal-spatial Deviation Index (Toddle TDI). 81 preterm children (≤32 weeks) with very-low-birth-weights (≤1500g) and 42 full-term TD children aged 18-22 months, adjusted for prematurity, walked on a pressure-sensitive mat. Preterm children were administered the Bayley Scales of Infant Development-3rd Edition (BSID-III). Principle component analysis of TD children's temporal-spatial gait parameters quantified raw gait deviation from typical, normalized to an average(standard deviation) Toddle TDI score of 100(10), and calculated for all participants. The Toddle TDI was significantly lower for preterm versus TD children (86 vs. 100, p=0.003), and lower in preterm children with <85 vs. ≥85 BSID-III motor composite scores (66 vs. 89, p=0.004). The Toddle TDI, which by design plateaus at typical average (BSID-III gross motor 8-12), correlated with BSID-III gross motor (r=0.60, p<0.001) and not fine motor (r=0.08, p=0.65) in preterm children with gross motor scores ≤8, suggesting sensitivity to gross motor development. The Toddle TDI demonstrated sensitivity and specificity to gross motor function in very-low-birth-weight preterm children aged 18-22 months, and has been potential as an easily-administered, revealing clinical gait metric.

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“…Neuere Studien weisen darauf hin, dass ± zumindest in den ersten Jahren ± bei VLBW-Kindern überwiegend medizinische Faktoren und nicht ein ungeeignetes oder wenig förderliches elterliches Milieu für die Entwicklung dieser Kinder verantwortlich ist [17,25,26]. Das Ausmaû der medizinischen bzw.…”

Section: Patienten Und Methodenunclassified

Der Einfluss prä-, peri- und neonataler Risikofaktoren auf die Entwicklung von Very-Low-Birth-Weight-Kindern im ersten Lebensjahr

Kohlhauser¹,

Fuiko²,

Brandstetter³

et al. 2001

Geburtsh u Frauenheilk

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ZusammenfassungFragestellung: Durch Fortschritte und Verbesserungen in der Geburtshilfe und der neonatologischen Intensivmedizin hat die Mortalität und Morbidität sehr kleiner Frühgeborener (VLBW) deutlich abgenommen; neurologische und psychomotorische Auffälligkeiten haben hingegen zugenommen. Die Bedeutung medizinischer und sozialer Risikofaktoren für den Entwicklungsverlauf von VLBW-Kindern wird unterschiedlich beurteilt. Ziel: Ziel unserer Studie war, den Einfluss prä-, peri-, neonataler und sozialer Risikofaktoren auf die motorische und kognitive Entwicklung von VLBW-Kindern im ersten Lebensjahr zu erfassen. Patienten und Methoden: Von 1994 ± 1997 wurden 451 VLBW-Kinder an der neonatologischen Intensivstation aufgenommen. 205 (56%) der überlebenden Kinder (mittleres Gestationsalter 28 2 SSW [23 ± 32], mittleres Geburtsgewicht 1020 270 g [465 ± 1500]) wurden in eine prospektive Nachuntersuchung eingeschlossen. Diese umfasste klinische, neurologische und entwicklungspsychologische Untersuchungen bis zum korrigierten Alter von 12 Monaten. Die Risikofaktoren von Kindern mit normaler Entwicklung oder leichter Entwicklungsbeeinträchtigung wurden mit jenen von Kindern mit schwerer Entwicklungsbeeinträchtigung (motorisch und/oder kognitiv) verglichen. Ergebnisse: Mit einer schweren Entwicklungsbeeinträchtigung waren assoziiert: (p < 0,05): Vaginale Geburt, Amnioninfektion, Geburtsgewicht £ 750 g, Gestationsalter £ 26 SSW, Surfactant, Indomethacintherapie bei offenem Ductus arteriosus Botalli, intraventrikuläre Blutung Grad III + IV, Sauerstoff > 28 Tage, broncho-Summary Purpose: Advances in obstetrics and neonatology over the last twenty years have resulted in decreased mortality and morbidity of VLBWI, however with increased rates of neurological and developmental impairments. The impact of medical and social risk factors to the overall outcome remains controversial. The purpose of our study was therefore to evaluate the impact of pre-, peri-, neonatal and social risk factors for poor neurodevelopmental outcome of VLBWI at one year of age. Patients and Methods: Between 1994 and 1997 451 VLBWI were admitted to the neonatal intensive care unit. 205 (56 %) of the surviving infants (mean gestational age 28 2 wks [23 ± 32], mean birth weight 1020 270 g [465 ± 1500]), have been enrolled in our prospective follow-up program. Neurological and developmental testing was performed within the first 12 months corrected for prematurity. Pre-, peri-, neonatal and social risk factors were compared between patients with a normal developmental outcome or mild developmental impairment and patients with severe impairment (neuromotor and/or cognitive). Results: Risk factors associated significantly with poor neurodevelopmental outcome (P £ 0.05): Vaginal delivery, chorioamnionitis, birth weight £ 750 g, gestational age £ 26 weeks, surfactant, therapy with indomethacin for patent ductus arteriosus (PDA), intraventricular hemorrhage III + IV, oxygen supply > 28 days, bronchopulmonary dysplasia, artificial ventilation > 8 days and length ...

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Outcome of Very-Low-Birth-Weight Infants at 1 and 2 Yearse of Age

Cited by 19 publications

References 22 publications

Early gross motor development of preterm infants according to the Alberta Infant Motor Scale

Early gross motor development of preterm infants according to the Alberta Infant Motor Scale

Toddle temporal-spatial deviation index: Assessment of pediatric gait

Der Einfluss prä-, peri- und neonataler Risikofaktoren auf die Entwicklung von Very-Low-Birth-Weight-Kindern im ersten Lebensjahr

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