Outcome of prenatally diagnosed mild unilateral cerebral ventriculomegaly.

Abstract

The objective of this study was to determine the frequency of prenatally diagnosed unilateral cerebral ventriculomegaly and also to assess neonatal outcome in infants with this prenatal diagnosis. A computerized ultrasonography database identified fetuses with isolated and nonisolated unilateral cerebral ventriculomegaly from October 1994 to June 1999. The Denver II Developmental Screening Test was used to assess developmental skills. Unilateral cerebral ventriculomegaly was diagnosed in 15 of 21,172 (1 per 1411) pregnancies. The width of the enlarged lateral ventricle ranged from 1.0 to 1.9 cm. In 10 (67%) of 15 cases unilateral cerebral ventriculomegaly was an isolated finding. Eight of the 14 infants who were born at 36 weeks' gestation or later had postnatal cranial imaging, and ventricular asymmetry was confirmed in 5 (63%). One infant with an arachnoid cyst and cerebral palsy died at 2 years of age. The remaining 11 infants in whom developmental milestones were assessed had age-appropriate skills. Unilateral fetal ventriculomegaly is usually an isolated finding and when isolated has little measurable effect on developmental outcome. Key words: neonatal outcome assessment; prenatal ultrasonographic diagnosis; unilateral cerebral ventriculomegaly.

The significance of fetal ventriculomegaly: etiology, short‐ and long‐term outcomes

“…As expected, improvement of VM is associated with a better outcome, while progression indicates a worse outcome (Arora et al, 1998;Gaglioti et al, 2005;Ouahba et al, 2006). On the contrary it seems that being the VM bilateral or unilateral does not affect the outcome (Lipitz et al, 1998;Senat et al, 1999;Durfee et al, 2001;Kinzler et al, 2001;Sadan et al, 2007). Pilu et al (1999) and Gaglioti et al (2005) found a prevalence of male fetuses with VM.…”

Unilateral cerebral ventriculomegaly: is one better than two?

“…The same gender differences did not hold true in cases of unilateral ventriculomegaly, inasmuch as male and female fetuses appeared to be evenly distributed. 2,3,6 When discussing normal fetal outcomes, however, we must determine how long the infants must be followed to ascertain full discovery of adverse outcomes. Most studies in the literature have follow-ups of a few months to a year or so, with normal milestones indicating a normal outcome.…”

Hidrocefalia Unilateral: Caso Clínico Y Revisión De La Literatura

“…La ecografía transvaginal se ha utilizado en el diagnóstico y evaluación de fetos que se encuentran en presentación cefálica. Este examen puede proporcionar una imagen más nítida de las estructuras anatómicas cerebrales (8).…”

“…En general, el pronóstico de hidrocefalia unilateral es favorable. En la mayoría de los estudios publicados los fetos con hidrocefalia unilateral sobreviven al período neonatal (2)(3)(4)8). El pronóstico depende en gran medida de la severidad de la dilatación ventricular y la presencia de otras anomalías cerebrales o extracraneales.…”

“…Descrita por primera vez por Von Mohr en 1842, es extremadamente infrecuente y rara vez detectada en el período prenatal (2,(5)(6)(7). La mayor serie publicada reporta una frecuencia de hidrocefalia unilateral de 0,07% (1 por 1.411 embarazos) (8). Es considerada una entidad distinta a la hidrocefalia bilateral, en cuanto a la mortalidad y pronóstico perinatal (2,3).…”