Outcome and Prognosis of Metastatic Brain Tumour: A Study of 35 Cases

Nath, Haradhan Deb; Barua, Kanak Kanti; Hossain, Mohammad Afzal; Khair, Abul; Islam, Aminul

doi:10.3329/bjn.v24i1.3036

Cited by 3 publications

(4 citation statements)

References 4 publications

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“…Headache and vomiting were noted as the two most common symptoms in many studies. Other symptoms noted here were also more or less similar to other studies 10,11,12,15 . But in a Polish study, the most frequent manifestation were psychic changes and neurological deficit signs (hemiperesis).…”

Section: Distribution Of the Symptomssupporting

confidence: 91%

Clinical Pattern of Intra-cranial space occupying lesion in Tertiary Level Hospital

et al. 2020

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Background : The term “Intra-cranial space occupying lesion” (ICSOL) is defined as any neoplasm, benign or malignant, primary or secondary, as well as any inflammatory or parasitic mass lying within the cranial cavity. Advances in intracranial imaging have made the detection of intracranial lesions relatively accurate and enabling us to focus on the etiology of these space-occupying lesions. Many reports suggested that both incidence and pattern of intracranial space occupying lesions are subject to considerable geographic and racial variations. Knowledge of the regional peculiarities of these lesions will help in identifications of possible risk factors. Materials and Methods: This observational study was done in the department of medicine of Mymensingh medical college hospital, Bangladesh from November, 2011 to April, 2012 to evaluate the clinical pattern of ICSOL among the 75 adult admitted patients. Patient aged more than 15 years of either sex with symptoms and signs of ICSOL and at least one CT or MRI evidence in favour of diagnosis were included. Results: The highest participation (22.7%) was observed from 55-64 years age group. Mean age of the participants was 54.35±18.68 years. Neoplastic tumor was (25.8%) in 15-24 years age group and non neoplastic lesion was (31.8%) in 55-64 years age group, among participants (76.0%) came from rural areas and 24% from urban. Population regarding the occupation 30.7% were housewives, 21.3% were service holders and 20.0% are farmers. Headache was the most common symptom noted in 93.33% of patients. Nausea/ vomiting, difficulty in limb movement and imbalance were the other most common three symptoms. In this series intracerebral hemorrhage was found in 53.3% of patients, Astrocytoma was the second most common (20.0%). Meningioma was found in 8% of the participants and another 8% had metastatic lesions in their brain. There were two cases of schwanoma while tuberculoma was diagnosed in another two participants (2.7%). Conclusion: Patients with symptoms and signs of ICSOL should be dealt with great care and CT or MRI helps to evaluate them for early diagnosis and proper management. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 17-22

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Section: Distribution Of the Symptomssupporting

confidence: 91%

Clinical Pattern of Intra-cranial space occupying lesion in Tertiary Level Hospital

et al. 2020

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“…Debnath et al . [ 17 ] showed that the highest occupational group were day laborers (31.43%) followed by service-holders (22.85%) and farmers (20%). In our study, 29.2% of patients were day laborer followed by service holder and farmer both constituting 20.8%, which correlates with above study.…”

Section: Discussionmentioning

confidence: 99%

“…Debnath et al . [ 17 ] in their study showed that in the majority of patients with brain metastases histology of the primary was adenocarcinoma (40.00%) followed by small cell carcinoma of lungs (28.57%) and squamous cell carcinoma (22.86%). In the present study in the majority of patients histology of primary malignancy was adenocarcinoma constituting 38.9%.…”

Section: Discussionmentioning

confidence: 99%

Demographic and clinical profile of patients with brain metastases: A retrospective study

et al. 2013

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Context:Brain metastases are the most common type of intracranial neoplasm, with the total number outnumbering primary brain tumors by a ratio of 10:1 and occur in about 25% of cancer patients. However, controversies exist regarding demographic and clinical profile of brain metastases.Aims:The purpose of this study was to analyze retrospectively the demographic and clinical profile of patients with brain metastases.Settings and Design:Retrospective, single institutional study.Materials and Methods:A retrospective study of 72 patients with brain metastasis was carried out from November 2010 to October 2012. The data pertaining to these patients was entered in a standardized case record form. These include History; clinical examination and other investigations including computed tomography/magnetic resonance imaging scan of the brain.Statistical Analysis:A statistical analysis was performed on the data collected using the MedCalc version 11.Results:Brain metastases were more common in male and occur in 6th decade of life mostly. There was no relationship of occupation or socio-economic status with the incidence of brain metastases. Carcinoma lung was the most common primary giving rise to brain metastases followed by breast. Adenocarcinoma accounts for most common histology of the primary that give rise to metastases. Multiple metastases were more common than the single group. Supratentorial lesions were more common than infratentorial lesions. Among them, parietal lobe was the most common site of involvement.Conclusions:The present study highlights that the incidence of brain metastasis is common in elderly population and mostly due to primary lung. Adenocarcinoma was the most common histology of primary. Majority of lesions has been observed at parietal lobe.

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“…Our study showed a female preponderance. The most common histologic subtype metastasizing to the brain is adenocarcinoma, followed by small cell lung carcinoma and squamous cell carcinoma (13,16,17) . Primary tumor histology remains unknown in 3 to 4% of patients (18) .…”

Section: Discussionmentioning

confidence: 99%

Clinical Profile of Metastatic Cancer to the Brain in a Tertiary Care Hospital

Kannan¹

2019

jmscr

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Outcome and Prognosis of Metastatic Brain Tumour: A Study of 35 Cases

Cited by 3 publications

References 4 publications

Clinical Pattern of Intra-cranial space occupying lesion in Tertiary Level Hospital

Clinical Pattern of Intra-cranial space occupying lesion in Tertiary Level Hospital

Demographic and clinical profile of patients with brain metastases: A retrospective study

Clinical Profile of Metastatic Cancer to the Brain in a Tertiary Care Hospital

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