Outbreak of Ochrobactrum anthropi endophthalmitis following cataract surgery

Abstract

Postoperative endophthalmitis often progresses to significant visual impairment. This paper describes an outbreak of Ochrobactrum anthropi endophthalmitis following cataract surgery, and propose a new sterilization protocol to minimize the risk of further cases. Medical records of patients with O. anthropi endophthalmitis or with suggestive clinical findings during the outbreak were reviewed. Seven cases of O. anthropi pseudophakic endophthalmitis were confirmed between 24 July and 10 November 2010. The most probable cause of the outbreak of Ochrobactrum anthropi endophthalmitis was contamination of the tubing of the phaco-emulsification machine. Following introduction of a new sterilization protocol, no further cases occurred in over 1000 subsequent procedures.

Ochrobactrum anthropiKeratitis with Focal Descemet’s Membrane Detachment and Intracorneal Hypopyon

“…and consists of ubiquitous aerobic, non-lactose-fermenting, glucose-oxidizing, gram-negative bacilli naturally found in soil, plants, and water. As such, these species have been identified in hospital water sources such as normal saline, antiseptic solutions, and dialysis liquids [ 1 , 3 – 5 ]. Ochrobactrum spp.…”

“…It was first reported in 1980 in a case of a pancreatic abscess [ 3 ] and has subsequently been identified in cases of urinary tract infection, pelvic abscess, infective endocarditis, peritonitis, osteomyelitis, and meningitis [ 1 ]. Additionally, many reported cases have been associated with indwelling medical devices such as central venous catheters, drainage tubes, and intraperitoneal catheters, likely due to the organism's ability to adhere to synthetic materials [ 4 , 5 ].…”

“…However, with improved speciation techniques, O. anthropi has now been implicated in a broad range of infections, even in immunocompetent hosts. There have been several reported cases of endophthalmitis in the literature but to our knowledge, O. anthropi has not been previously identified as a cause of keratitis [ 5 ]. We describe a unique case of O. anthropi associated keratitis with focal Descemet's membrane detachment and intracorneal hypopyon formation in the setting of longstanding herpetic eye disease.…”

Seleção de marcadores para a busca ativa de endoftalmite após cirurgia de catarata

“…A cirurgia de correção de catarata, ou facectomia, está associada a várias complicações pós-operatórias, incluindo a infecção intraocular, conhecida como endoftalmite. Os sinais clínicos de endoftalmite são frequentemente observados nos primeiros sete dias após a cirurgia 1,2 . Os sinais e sintomas mais comuns são: reação da câmara anterior, hipópio, edema de pálpebras e da córnea [3][4][5] , hiperemia conjuntival e vítreo turvo 1,4,6 .…”

Pesquisa de infecção por Brucella spp. em botos-vermelhos (Inia geoffrensis) de vida livre, procedentes da reserva de desenvolvimento sustentável de Mamirauá, Tefé, Amazonas, Brasil

“…O teste laboratorial considerado "padrão ouro" para o diagnóstico da brucelose é o cultivo microbiológico para isolamento de Brucella spp. O gênero Brucella tem sido considerado um gênero bacteriano em expansão, em razão das novas variantes e espécies identificadas em várias espécies de hospedeiros silvestres nas últimas décadas (BARUN et al, 2007;FOSTER et al, 2007;SCHLABRITZ-LOUTSEVITCH et al, 2009;SCHOLZ et al, 2009SCHOLZ et al, , 2010EISENBERG et al, 2013 HUBER et al, 2010), vegetais (TRUJILLO et al, 2005TRIPATHI et al, 2006;ZURDO-PINERO et al, 2007;KAMPFER et al, 2008;IMRAN et al, 2010), plantas de tratamento de esgotos e águas residuárias WOO et al, 2011), humanos (MOLLER et al, 1999;MAHMOOD et al, 2000;STIAKAKI et al, 2002;TEYSSIER et al, 2007;DHARNE et al, 2008;HAGIYA et al, 2013;MATTOS et al, 2013; SITI ROHANI E TZAR, 2013) e animais (KAMPFER et al, 2003(KAMPFER et al, , 2011EL ADAWY et al, 2012). Algumas espécies do gênero vêm sendo estudadas pelo potencial de aplicação como biorremediadores ou como bactérias promotoras de crescimentos para plantas (PANDEY et al, 2013 (MOLLER et al, 1999;MAHMOOD et al, 2000;STIAKAKI et al, 2002;DHARNE et al, 2008;HAGIYA et al, 2013;MATTOS et al, 2013;ROHANI;TZAR, 2013 (ELSAGHIR et al, 2003;HOVART et al, 2011 Atualmente, a família Propionibacteriaceae é composta por 15 gêneros bacterianos: Propionibacterium (CH...…”