“…17 A thorough analysis released in August 2020 discovered that COVID-19 patients with high D-dimer values had a greater risk of fatal illness and severe sickness, and it also indicated that no reliable cutoff value had been established to predict adverse effects. 18 In this study, we also found that an elevated ferritin levels were associated with a poor prognosis. The mechanism could be possibly explained by the presence of secondary hemophagocytic lymphohistiocytosis in these patients.…”
According to the existing evidence, inflammatory reactions appear to have a significant impact on the emergence of COVID-19. This study aims to determine the severity of COVID-19-associated laboratory measures, particularly in patients receiving non-invasive ventilation. METHOD: This observational study involved 150 patients who were on non-invasive ventilation and tested positive for the Covid19 RTPCR/GENEXPERT gene. C reactive protein, D dimer, and ferritin examinations were frequently collected and Data were entered. Microsoft Excel, and SPSS software version 17.0 was used for the statistical analysis. The components of descriptive statistics are mean, standard deviation, frequency, and percentage. Student T-test was used to evaluate CRP, D Dimer, and ferritin between covid positive patients' outcome variables P<0.05 significant analysis will be done using SPSS software version 25. Result: CRP levels were above 10; 131 patients with bad outcomes (59) and 73 patients (55.7) survived. Thirty-five patients (39%) and 55 patients (61%) with D-dimer values of 1 survived. 64 Patients (50.8%) with ferritin levels of more than 300 survived, while 62 Patients (48%) died. Conclusion: In our study population, elevated ferritin and D-dimer levels were found to be related to bad outcomes, whereas elevated CRP levels did not.
“…17 A thorough analysis released in August 2020 discovered that COVID-19 patients with high D-dimer values had a greater risk of fatal illness and severe sickness, and it also indicated that no reliable cutoff value had been established to predict adverse effects. 18 In this study, we also found that an elevated ferritin levels were associated with a poor prognosis. The mechanism could be possibly explained by the presence of secondary hemophagocytic lymphohistiocytosis in these patients.…”
According to the existing evidence, inflammatory reactions appear to have a significant impact on the emergence of COVID-19. This study aims to determine the severity of COVID-19-associated laboratory measures, particularly in patients receiving non-invasive ventilation. METHOD: This observational study involved 150 patients who were on non-invasive ventilation and tested positive for the Covid19 RTPCR/GENEXPERT gene. C reactive protein, D dimer, and ferritin examinations were frequently collected and Data were entered. Microsoft Excel, and SPSS software version 17.0 was used for the statistical analysis. The components of descriptive statistics are mean, standard deviation, frequency, and percentage. Student T-test was used to evaluate CRP, D Dimer, and ferritin between covid positive patients' outcome variables P<0.05 significant analysis will be done using SPSS software version 25. Result: CRP levels were above 10; 131 patients with bad outcomes (59) and 73 patients (55.7) survived. Thirty-five patients (39%) and 55 patients (61%) with D-dimer values of 1 survived. 64 Patients (50.8%) with ferritin levels of more than 300 survived, while 62 Patients (48%) died. Conclusion: In our study population, elevated ferritin and D-dimer levels were found to be related to bad outcomes, whereas elevated CRP levels did not.
“…People who put on weight during the lockdown also had a more sedentary lifestyle most of the time - watching television and doing on-screen leisure activities, using smartphones, the internet, or socializing online. This weight gain related to COVID-19 will cause an increased risk of developing metabolic disorders in the population with a previous diagnosis of disease [ 30 ], but also in the population who had not suffered from these disorders beforehand [ 31 ]. Moreover, it has been observed that the population with previous pathology has a higher risk of becoming severely ill if infected by the virus [ 31 , 32 ].…”
Section: Introductionmentioning
confidence: 99%
“…This weight gain related to COVID-19 will cause an increased risk of developing metabolic disorders in the population with a previous diagnosis of disease [ 30 ], but also in the population who had not suffered from these disorders beforehand [ 31 ]. Moreover, it has been observed that the population with previous pathology has a higher risk of becoming severely ill if infected by the virus [ 31 , 32 ].…”
In December 2019, 27 cases of pneumonia were reported in Wuhan. In 2020, the causative agent was identified as a virus called SARS-CoV-2. The disease was called “coronavirus disease 2019” (COVID-19) and was determined as a Public Health Emergency. The main measures taken to cope with this included a state of lockdown. The aim of this study was to assess how the unhealthy lifestyles that ensued influenced different parameters. A prospective study was carried out on 6236 workers in a Spanish population between March 2019 and March 2021. Anthropometric, clinical, and analytical measurements were performed, revealing differences in the mean values of anthropometric and clinical parameters before and after lockdown due to the pandemic, namely increased body weight (41.1 ± 9.9–43.1 ± 9.9), BMI (25.1 ± 4.7–25.9 ± 4.7), and percentage of body fat (24.5 ± 9.1–26.9 ± 8.8); higher total cholesterol levels, with a statistically significant increase in LDL levels and a reduction in HDL; and worse glucose levels (90.5 ± 16.4–95.4 ± 15.8). Lockdown can be concluded to have had a negative effect on health parameters in both sexes in all age ranges, causing a worsening of cardiovascular risk factors.
“…The outbreak of coronavirus disease 2019 (COVID- 19) represented a new worldwide challenge, strongly impacting on the global economy, overall health and lifestyle. 1 Since then, several strategies have been adopted to contain the widespread of infection. 2,3 Dermatologists played a key role during the pandemic, fighting against several challenges such as cutaneous reactions caused by COVID-19 disease, the hesitancy on the efficacy and safety of conventional treatment and biologic drugs in this period, the worsening of several dermatosis due to the wearing of personal protection equipment and the introduction of a new lifestyle.…”
Section: Introductionmentioning
confidence: 99%
“…(1). Merhy et al62 (1), Camela et al63 (1), Kato et al69 (1), Diab et al70 (1), Zagaria et al71 (1), Awada et al72 (1), Picone et al73 (1), Hlaca et al74 (1), Zengarini et al75 (1), Masseran et al76 (1), Gamonal et al64 (1), Alrawashdeh et al65 (1), Shakoei et al66 (1).…”
The outbreak of coronavirus disease 2019 represented a new worldwide challenge, strongly impacting on the global economy, overall health and lifestyle. Since then, several strategies have been adopted to contain the widespread of infection. Among these, vaccination is currently the most important measure to fight against the pandemic. However, several concerns such as slower-than-hoped-for rollout, the hurried approval with limited data, the mechanism of action (in particular mRNA-based), and the uncertain duration of protection they afforded were initially raised. Moreover, even if cutaneous reactions have been rarely reported in clinical trials, global mass vaccination showed several dermatologic reactions not initially recognized, leaving dermatologists to decide how to diagnose and treat them. In this scenario, dermatologists should be ready to promptly recognize these clinical manifestations. Thus, the aim of this manuscript is to review current literature on cutaneous reactions following COVID-19 vaccination, particularly inflammatory dermatological diseases, in order to help clinicians to better understand these dermatological conditions and to provide an extensive overview of all the vaccine-related skin manifestations.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.