Out With the Old, in With the New: Replacing the “6-Month Abstinence Rule” With Integrated Care for Alcohol-Associated Liver Disease

German, Margarita N.; Brown, Randall; Lucey, Michael R.

doi:10.1053/j.gastro.2021.09.041

Cited by 2 publications

(1 citation statement)

References 20 publications

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“…Most people with ALD receive no or insufficient treatment for AUD. 83 One aspect of this alignment would be replacing rigid abstinence requirements before liver transplantation with more nuanced psychosocial assessments of prognostic factors for the underlying AUD, 84,85 thus reducing structural stigma. This is also reflected in recommendations of both the European Association for the Study of the Liver 86 and the American Association for the Study of Liver Diseases.…”

Section: Structural Changesmentioning

confidence: 99%

The stigma of alcohol-related liver disease and its impact on healthcare

Schomerus

Leonhard

Manthey

et al. 2022

Journal of Hepatology

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Section: Structural Changesmentioning

confidence: 99%

The stigma of alcohol-related liver disease and its impact on healthcare

Schomerus

Leonhard

Manthey

et al. 2022

Journal of Hepatology

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Integrated and collaborative care across the spectrum of alcohol-associated liver disease and alcohol use disorder

Haque,

Leggio

2024

Hepatology

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The public health impact of alcohol-associated liver disease (ALD), a serious consequence of problematic alcohol use, and alcohol use disorder (AUD) is growing, with ALD becoming a major cause of alcohol-related death overall and the leading indication for liver transplantation in the United States. Comprehensive care for ALD often requires treatment of AUD. Although there is a growing body of evidence showing that AUD treatment is associated with reductions in liver-related morbidity and mortality, only a minority of patients with ALD and AUD receive this care. Integrated and collaborative models that streamline both ALD and AUD care for patients with ALD and AUD are promising approaches to bridge this treatment gap and rely on multidisciplinary and interprofessional teams and partnerships. Here, we review the role of AUD care in ALD treatment, the effects of AUD treatment on liver-related outcomes, the impact of comorbid conditions such as other substance use disorders, obesity, and metabolic syndrome, the current landscape of integrated and collaborative care for ALD and AUD in various treatment settings. We further review knowledge gaps and unmet needs that remain, including the role of precision medicine, the application of harm reduction approaches, the impact of health disparities, the need for additional AUD treatment options as well as further efforts to support implementation and dissemination.

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Out With the Old, in With the New: Replacing the “6-Month Abstinence Rule” With Integrated Care for Alcohol-Associated Liver Disease

Cited by 2 publications

References 20 publications

The stigma of alcohol-related liver disease and its impact on healthcare

The stigma of alcohol-related liver disease and its impact on healthcare

Integrated and collaborative care across the spectrum of alcohol-associated liver disease and alcohol use disorder

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