Otomycosis

Edward, Yan; Irfandy, Dolly

doi:10.25077/jka.v1i2.59

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…The surface of healthy EAC skin harbors various microbial species, including St aphylococcus spp., Corynebacterium spp., Bacillus spp., Streptococcus spp., Gram-negative bacilli (e.g., Pseudomonas aeruginosa , Escherichia coli ), as well as fungi, predominantly of the Aspergillus and Candida species [ 21 ]. The saprophytic nature of these microorganisms can become pathogenic if the balance between bacterial and fungal growth is disrupted, especially if non-specific and specific body defense mechanisms are compromised [ 22 , 23 ].…”

Section: Pathogenesis Of Otomycosismentioning

confidence: 99%

Etiology, Predisposing Factors, Clinical Features and Diagnostic Procedure of Otomycosis: A Literature Review

Bojanović

Stalević²,

Arsenijevic

et al. 2023

JoF

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Otomycosis (OM) is a superficial fungal infection of the external auditory canal (EAC) with a worldwide prevalence ranging from 9% to 30%. Commonly, otomycoses are caused by Aspergillus (A.) niger complex and Candida spp. Other causative agents are yeasts of the genera Cryptococcus spp., Rhodotorula spp., Geotrichum candidum, dermatophytes (Trichophyton mentagrophytes), and non-dermatophytes molds (Fusarium spp., Penicillium spp., Mucorales fungi). The widest range of different species causing OM are found in the territories of Iran, India, China, Egypt, Mexico, and Brazil. Fungal infection of the EAC varies from mild to severe forms. It can be acute, subacute, or chronic, and is often unilateral, while the bilateral form is more common in immunocompromised patients. From an epidemiological point of view, tropical and subtropical climates are the most significant risk factor for the development of otomycosis. Other predisposing conditions include clothing habits, EAC hygiene practices, long-term antibiotic therapy, diabetes, and immunodeficiency. Since it is often difficult to distinguish otomycosis from an infection of a different origin, laboratory-based evidence, including standard procedures (microscopy and cultivation), is essential for diagnosis. For the treatment of this superficial fungal infection, there are no official therapeutic guidelines and protocols. However, many antifungals for local application, such as polyene, imidazoles, and allylamines, can be applied, as well as systemic antimycotics (triazoles) in severe forms of infection.

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Section: Pathogenesis Of Otomycosismentioning

confidence: 99%

Etiology, Predisposing Factors, Clinical Features and Diagnostic Procedure of Otomycosis: A Literature Review

Bojanović

Stalević²,

Arsenijevic

et al. 2023

JoF

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Fungal otitis externa in children: principles of diagnosis and rational therapy

Kryukov¹,

Kunelskaya²,

Kunel’skaya

et al. 2020

Vestn. otorinolaringol.

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Uji Efektivitas Ekstrak Metanol Buah Pare (Momordica Charantia L.) Terhadap Pertumbuhan Aspergillus Niger

Ilham¹,

Ika²,

Mega³

2022

BIGES JUKES

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Aspergillus niger is a species of fungus from the genus Aspergillus which is reported to be the main cause of otomycosis. Bitter gourd (Momordica charantia L.) contains several compounds, namely phenols, flavonoids, triterpenoids, steroids, saponins, and alkaloids that have potential as antifungals. This study aims to determine the content of phytochemical compounds present in the methanol extract of bitter melon and to test the effectiveness of the methanol extract of bitter melon on the growth of Aspergillus niger through the MIC test. This study used an in vitro laboratory experimental research design with a post-test-only control group design method. The MIC test used the multilevel serial microdilution method which was observed visually. The extract concentrations used were 8000 µg/ml, 4000 µg/ml, 2000 µg/ml, 1000 µg/ml, 500 µg/ml, 250 µg/ml, 125 µg/ml, and 62.5 µg/ml. The fruit samples of this study was bitter gourd obtained from bitter gourd farmers in Bandungan District, Semarang Regency, and pure culture of Aspergillus niger FNCC 6018. Data analysis used descriptive analysis. The results of the phytochemical screening showed positive saponins, flavonoids, and phenolic compounds, and the MIC value was not found. It was concluded that the methanol extract of bitter melon was not effective in inhibiting the growth of Aspergillus niger.

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Otomycosis

Cited by 3 publications

References 5 publications

Etiology, Predisposing Factors, Clinical Features and Diagnostic Procedure of Otomycosis: A Literature Review

Etiology, Predisposing Factors, Clinical Features and Diagnostic Procedure of Otomycosis: A Literature Review

Fungal otitis externa in children: principles of diagnosis and rational therapy

Uji Efektivitas Ekstrak Metanol Buah Pare (Momordica Charantia L.) Terhadap Pertumbuhan Aspergillus Niger

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