Fungal otitis externa in children: principles of diagnosis and rational therapy

Kryukov, A. I.; Kunelskaya, N. L.; Kunel’skaya, V. Ya.; Ivoylov, A Yu; Шадрин, Г Б; Machulin, A I

doi:10.17116/otorino20208501160

Cited by 3 publications

(1 citation statement)

References 1 publication

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“…Otitis externa is a superficial fungal infection that can involve the middle ear, which is affected in more than 10% of all otitis externa cases ( 1 ). Bacterial infections of the ears are usually acute, while mycotic infections may be acute or subacute and cause inflammation and itching ( 2 ). Severe infections are generally caused by bacteria and may lead to the secretion of pus.…”

Section: Introductionmentioning

confidence: 99%

A Comparison of Antifungal Drugs and Traditional Antiseptic Medication for Otomycosis Treatment: A Systematic Review and Meta-Analysis

Cheng

Lin

et al. 2021

Front. Surg.

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Objectives/Hypothesis: To perform a systematic review and meta-analysis to compare the efficacy of and complications associated with antifungal drugs and traditional antiseptic medication for the treatment of otomycosis.Data Sources: The PubMed, EMBASE, GeenMedical, Cochrane Library, CBM, CNKI, VIP and other databases were searched from January 1991 to January 2021.Methods: The systematic literature review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Randomized controlled trials (RCTs) and non-randomized studies (case-control, cohort, and case series) were included to assess the topical use of antifungal drugs and traditional antiseptic medication in patients with otomycosis. The research subjects were patients who were clinically diagnosed with otomycosis and whose external auditory canal secretions were positive for fungi. Funnel plots were used to detect bias, and the Q test was used to assess heterogeneity. The random-effects model was used for meta-analysis. The t-test was used to assess significance.Results: Of the 324 non-duplicate studies screened, 16 studies met the criteria for full-text review, and 7 were included in the meta-analysis. Four studies reported recovery conditions (P = 0.01). Six common complications after medication use were compared, and there were no significant differences. The authors further conducted subgroup analysis according to complications. The differences in the rates of ear distension (P = 0.007), earache (P = 0.03) and tinnitus (P = 0.003) were statistically significant.Conclusion: The results of this meta-analysis and literature review showed that antifungal drugs and traditional antiseptic medication were effective in relieving symptoms in patients with otomycosis, and the two treatments were associated with different complications. Otolaryngologists have the option to use one medication or a combination of two drugs on the basis of the condition. Future research in this area should include RCTs with long-term follow-up to guide the development of otomycosis guidelines to overcome some of the weaknesses found in the literature.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO/#myprospero.

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Section: Introductionmentioning

confidence: 99%

A Comparison of Antifungal Drugs and Traditional Antiseptic Medication for Otomycosis Treatment: A Systematic Review and Meta-Analysis

Cheng

Lin

et al. 2021

Front. Surg.

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Treatment of chronic eczematous otitis externa

Kunel’skaya¹,

Ivoylov²,

Mileshina³

et al. 2022

Vestn. otorinolaringol.

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External otitis media: modern possibilities for improving the effectiveness of treatment and the quality of life of patients

Korkmazov,

Gizinger,

Kornova

et al. 2024

Medicinskij sovet

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Introduction. Polyethologicity of otitis externa with inflammation of the auricle, ear canal and outer layer of the eardrum, persistent course and high probability of recurrence necessitates improved treatment.Aim. To evaluate the effectiveness of the use and the impact on the quality of life of combined ear drops with antimicrobial and local anesthetic effects.Materials and methods. A simple randomized controlled clinical trial involved 56 people, including 25 women and 31 men aged 32 to 56 years, suffering from acute diffuse otitis externa. Clinical efficacy, recovery time and impact on quality of life were evaluated in two groups: groups 1 (n = 27), patients receiving ear drops containing choline acetate as local therapy, with group 2 (n = 29) taking a multicomponent drug containing polymyxin B sulfate 1,000,000 IU, neomycin sulfate 0.5 g (375,000 IU) and lidocaine hydrochloride in the form of ear drops. The assessment of otalgia, hearing loss and discharge from the external auditory canal was carried out on the VAS, quality of life scale using the SF-36 general questionnaires.Results and discussion. There was a positive dynamic of clinical manifestations and restoration of quality-of-life indicators in a shorter period (3rd, 5th day) with the disappearance of all the main clinical symptoms (7th day) with good tolerability and absence of side effects in the second group of patients taking the multicomponent drug.Conclusions. The use of ear drops containing a combination of topical antimicrobial drugs with an anesthetic in the complex therapy of otitis externa significantly improved the clinical symptoms and quality of life of patients.

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Fungal otitis externa in children: principles of diagnosis and rational therapy

Cited by 3 publications

References 1 publication

A Comparison of Antifungal Drugs and Traditional Antiseptic Medication for Otomycosis Treatment: A Systematic Review and Meta-Analysis

A Comparison of Antifungal Drugs and Traditional Antiseptic Medication for Otomycosis Treatment: A Systematic Review and Meta-Analysis

Treatment of chronic eczematous otitis externa

External otitis media: modern possibilities for improving the effectiveness of treatment and the quality of life of patients

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