2004
DOI: 10.1111/j.1939-165x.2004.tb00356.x
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Osteosarcoma with multiple metastases and subcutaneous involvement in a rabbit (Oryctolagus cuniculus)

Abstract: Clinical, radiologic, and pathologic data supported a diagnosis of osteosarcoma with multiple metastases and subcutaneous involvement.

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Cited by 25 publications
(15 citation statements)
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“…Metaplastic bone formation differentiates this tumour from osteosarcoma, which has been reported as an unusual spontaneous event in older rabbits (Mazzullo et al, 2004), where it may arise in long and flat bones (Hoover et al, 1986;Kondo et al, 2007), may metastasize (Walberg, 1981) and, most importantly, may cross joint spaces, resulting in a presentation similar to the present case (Kondo et al, 2007).…”
supporting
confidence: 56%
“…Metaplastic bone formation differentiates this tumour from osteosarcoma, which has been reported as an unusual spontaneous event in older rabbits (Mazzullo et al, 2004), where it may arise in long and flat bones (Hoover et al, 1986;Kondo et al, 2007), may metastasize (Walberg, 1981) and, most importantly, may cross joint spaces, resulting in a presentation similar to the present case (Kondo et al, 2007).…”
supporting
confidence: 56%
“…[7][8][9][10][11][12][13][14][15] We are aware of only rare published case reports in animals, including primary bone OSA with cutaneous metastasis in a dog 4 and 2 rabbits with subcutaneous OSA attributed to presumed metastasis from primary bone OSA. 6,7 In the canine case, a 3-year-old, male Rottweiler was presented with multiple cutaneous metastases (sites unspecified) secondary to OSA in the distal left femur. Radiographic evidence of tumor invasion at other sites was not identified at the time of initial diagnosis; however, widespread metastatic disease was present at necropsy.…”
Section: Discussionmentioning
confidence: 99%
“…A few reports [13][14][15] of osteosarcoma in rabbits exist, but there has been only 1 report 16 of fractures attributed to metastases of uterine adenocarcinoma to bone tissue. A few reports [13][14][15] of osteosarcoma in rabbits exist, but there has been only 1 report 16 of fractures attributed to metastases of uterine adenocarcinoma to bone tissue.…”
Section: Small Animals/ Exoticmentioning
confidence: 99%