Osteoporosis Risk Factors and Early Life-style Modifications to Decrease Disease Burden in Women

Nachtigall, Margaret J.; Nazem, T.G.; Nachtigall, Richard; Goldstein, Steven R.

doi:10.1097/grf.0b013e3182aa1daf

Cited by 19 publications

(12 citation statements)

References 4 publications

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“…Early-life conditions are increasingly recognized as playing an important role in the etiology of chronic diseases (23), including coronary heart disease (24–26) and cardiac dysfunction (27), type-2 diabetes (28–30), chronic obstructive pulmonary disease (31–33), asthma (34), osteoporosis (35–37), and hypertension (38, 39). In addition, social and material disadvantages experienced in early-life have been associated with poor health behaviors in adulthood, such as smoking and excessive alcohol consumption (40–42), obesity (42–44), and poor overall mental and physical health (45).…”

Section: Introductionmentioning

confidence: 99%

Baby Boomers and Birth Certificates: Early-Life Socioeconomic Status and Cancer Risk in Adulthood

Stroup

Herget

Hanson

et al. 2017

Cancer Epidemiology, Biomarkers &Amp; Prevention

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BACKGROUND Early life socioeconomic status (SES) may play a role in cancer risk in adulthood. However, measuring SES retrospectively presents challenges. Parental occupation on the birth certificate is a novel method of ascertaining early-life SES that has not been applied in cancer epidemiology. METHODS For a Baby-Boom cohort born in 1945–1959 in two Utah counties, individual-level Nam-Powers SES (Np-SES) was derived from parental industry/occupation reported on birth certificates. Neighborhood SES was estimated from average household income of census tract at birth. Cancer incidence was determined by linkage to Utah Cancer Registry records through the Utah Population Database. Hazard ratios (HR) for cancer risk by SES quartile were estimated using Cox proportional hazards regression. RESULTS Females with low Np-SES at birth had lower risk of breast cancer compared to those in the highest Np-SES group (HRQ1/Q4=0.83 95% CI: 0.72–0.97; HRQ2/Q4=0.81 95% CI: 0.69–0.96). Np-SES was inversely associated with melanoma (HRQ1/Q4=0.81 95% CI: 0.67–0.98) and prostate cancer (HRQ1/Q4=0.70 95% CI: 0.56–0.88). Women born into lower SES neighborhoods had significantly increased risk for invasive cervical cancer (HRQ1/Q4=1.44 95% CI: 1.12–1.85; HRQ2/Q4=1.33 95% CI: 1.04–1.72). Neighborhood SES had similar effects for melanoma and prostate cancers, but was not associated with female breast cancer. We found no association with SES for pancreas, lung, and colon and rectal cancers. CONCLUSION Individual SES derived from parental occupation at birth was associated with altered risk for several cancer sites. IMPACT This novel methodology can contribute to improved understanding of the role of early-life SES in affecting cancer risk.

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Section: Introductionmentioning

confidence: 99%

Baby Boomers and Birth Certificates: Early-Life Socioeconomic Status and Cancer Risk in Adulthood

Stroup

Herget

Hanson

et al. 2017

Cancer Epidemiology, Biomarkers &Amp; Prevention

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“…[6][7][8] Other protective lifestyle behaviors include consuming adequate energy through a well-balanced and nonrestrictive diet, exercising regularly, limiting excessive alcohol consumption, and avoiding smoking. 2,[9][10][11][12][13][14] Although bone mass develops and peaks during adolescence and early adulthood, adequate maintenance throughout adulthood is necessary to reduce the rate of natural bone loss and offset the effects of osteoporosis in later years. 15,16 Although Hispanic and non-Hispanic white women experience similar rates of low bone mineral density and osteoporosis, diet behaviors that impact bone health are less commonly examined in Hispanic women.…”

mentioning

confidence: 99%

Lifestyle Behaviors Affecting Bone Health in Young Hispanic and Non-Hispanic White Women

Berube

Heller

Milliron

et al. 2016

Topics in Clinical Nutrition

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Osteoporosis afflicts a large population of older women in the United States and has major impacts on morbidity and mortality. Previously, non-Hispanic white women were believed to be at greatest risk of osteoporosis, but current research suggests that Hispanic women are of similar risk. While risk increases with age and is influenced by genetics, lifestyle behaviors throughout the life cycle contribute to disease prevention. Our results found no differences in bone mineral density, dietary characteristics, or physical activity between young Hispanic and non-Hispanic white women. However, both groups failed to meet, but should engage in, recommended practices for bone health maintenance.

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“…-Ensure adequate calcium and vitamin D intake -Decrease alcohol, caffeine and tobacco consumption -Encourage regular physical activity [39] -Fall prevention, with a home safety evaluation, if indicated [31,40] Recommending the use of calcium and vitamin D supplementation is an easy and relatively inexpensive intervention that can be applied to the vast majority of people encountered after a fragility fracture. There are good meta-analyses on the fracture risk reduction of calcium and vitamin D supplementation, with the corollary that the benefit might be seen more in institutionalised individuals more so than in communitydwelling individuals [41][42][43].…”

Section: Early Interventions That Can Be Driven By the Orthopaedistmentioning

confidence: 99%

Osteoporosis and the orthopaedic surgeon: basic concepts for successful co-management of patients’ bone health

Farmer

Herbert

Cuellar

et al. 2014

International Orthopaedics (SICOT)

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Osteoporosis has been recognised as a public health concern for at least three decades but it has been relatively recent that the push has been for orthopaedic surgeons to take a more active role in the diagnosis and treatment of patients with decreased bone mineral density (BMD). Most often these patients are encountered after they have suffered a fracture making secondary prevention the area where orthopaedists may exert the greatest influence on patient care. The purpose of this article is to provide a succinct framework for the diagnosis and treatment of patients with decreased BMD. Patients are deemed to have decreased BMD if they have suffered a fragility fracture, a fracture caused by a lowenergy traumatic event. These patients are often encountered in the emergency department and admitted for further treatment of their fractures or recommended for follow-up in the clinic. Regardless of treatment course these are opportunities for the orthopaedic surgeon to intervene in the osteoporotic disease process and positively affect a patient's bone health. This article compiles the available literature on osteoporosis and presents it succinctly with the incorporation of both a diagnosis algorithm and treatment profile table. With the use of these two tools, orthopaedic surgeons everywhere should be able to take a more active role in their patients' bone health.

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Osteoporosis Risk Factors and Early Life-style Modifications to Decrease Disease Burden in Women

Cited by 19 publications

References 4 publications

Baby Boomers and Birth Certificates: Early-Life Socioeconomic Status and Cancer Risk in Adulthood

Baby Boomers and Birth Certificates: Early-Life Socioeconomic Status and Cancer Risk in Adulthood

Lifestyle Behaviors Affecting Bone Health in Young Hispanic and Non-Hispanic White Women

Osteoporosis and the orthopaedic surgeon: basic concepts for successful co-management of patients’ bone health

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