Osteoinduction of bone grafting materials for bone repair and regeneration

García‐Gareta, Elena; Coathup, Melanie; Blunn, Gordon

doi:10.1016/j.bone.2015.07.007

Cited by 504 publications

(395 citation statements)

References 162 publications

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“…Collagen is most widespread protein in the body occurring in most connective tissues as skin, tendon and bone 1,2 . Collagen consists of three parallel polypeptide strands in a left-handed, polyproline II-type helical conformation coil about each other with a one-residue stagger to form a right-handed triple helix.…”

Section: Introductionmentioning

confidence: 99%

Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

Rizk¹,

Mostafa²

2016

Orient. J. Chem

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Collagen is widely used for biomedical and pharmaceutical applications due to its excellent biocompatibility, biodegradability and weak antigenicity. However, applicability is limited due to its high cost and probability of disease transmission from the current sources, which are bovine and porcine. In the present study, collagen was extracted from 6 months buffalo skins as alternative save sources. Collagen was characterized by different physico-chemical techniques like ATR-FTIR, Raman, SEM, DSC and amino acids analysis. Proline and hydroxyproline contents of buffalo skin collagen were higher than those of calf skin collagen. Thermal stability of buffalo skin collagen is high with respect to that of calf skin collagen. The obtained buffalo skin collagen shows higher stiffness upon cross-linking with glutaraldehyde. Thus buffalo skin collagen can be used for fabrication of high strength bioactive sponge and sheets for medical applications, like scaffold for tissue engineering, drug delivery and wound dressing system.

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Section: Introductionmentioning

confidence: 99%

Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

Rizk¹,

Mostafa²

2016

Orient. J. Chem

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“…These disadvantages can be eliminated by the use of allografts, which are obtained from living donors or tissue banks. Despite increased availability and donor site morbidity disposal, this type of graft is associated with the transmission of diseases, bacterial infection, and immune rejection, in addition to presenting a limited osteoconductiveness [11]. Thus, the creation of the ideal material for bone replacement is necessary [20].…”

Section: Discussionmentioning

confidence: 99%

Stem cells carrier scaffolds for tissue engineering

Lopes

Levandowski

Fonseca

et al. 2017

RSBO

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“…Its structure is organized and comprise ligands that can be bound to cell receptors. [18,81,82]. Although in some cases (e.g.…”

Section: Natural Polymersmentioning

confidence: 99%

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Neto¹,

Ferreira²

2018

Preprint

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Bone is a dynamic tissue with the capacity of repair and regeneration in specific conditions. Nevertheless, due to the increased incidence of bone disorders, the need of bone grafts has been growing over the past decades and the development of a bone graft with optimal properties remains a clinical challenge. This review addresses the bone properties (morphology, composition and their repair and regeneration capacity) and then is focused on the potential strategies for bone repair and regeneration. It describes the requirements for designing a suitable scaffold material, types of materials (polymers, ceramics and composites) and techniques to obtain the porous structures (additive manufacturing techniques/robocasting or derived from marine skeletons) for bone tissue engineering applications. The main objective of this review is to gather the knowledge on the materials and methods for the production of scaffolds for bone tissue engineering and highlight that natural materials, namely the marine skeletons represent a promising alternative.

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Osteoinduction of bone grafting materials for bone repair and regeneration

Cited by 504 publications

References 162 publications

Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

Stem cells carrier scaffolds for tissue engineering

Synthetic and Marine-Derived Porous Bone Graft Substitutes

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