Osteoid osteomas of the femoral neck: report of four cases evaluated with isotopic bone scanning, CT, and MR imaging.

Goldman, Amy Beth; Schneider, Robert J.; Pavlov, Helene

doi:10.1148/radiology.186.1.8416569

Cited by 88 publications

(49 citation statements)

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“…No cases associated with synovitis in the adjacent joints have been reported in which the nidus is located in diaphysis of the long bones. Surgical removal of the nidus has been reported to result in remission of synovitis (10,27). As previously reported, in our control Cases 5 to 7, diaphyseal lesions were not associated with synovitis.…”

Section: Discussionsupporting

confidence: 85%

“…CassarPullicino et al (9) reported that synovitis in the involved joint occurred in 25% of tumors evaluated by surgical findings. Magnetic resonance imaging (MRI) showed pooling of joint effusion in all cases of intraarticular OO (10). Histologic examination further confirmed the presence of prominent nonspecific chronic synovitis or lymphofollicular synovitis, resembling rheumatoid arthritis (RA), in the joint with intraarticular OO (11).…”

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confidence: 87%

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Intraarticular Osteoid Osteoma Associated with Synovitis: A Possible Role of Cyclooxygenase-2 Expression by Osteoblasts in the Nidus

Kawaguchi

Sato

Hasegawa³

et al. 2000

Modern Pathology

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To clarify the condition of development of synovitis associated with intraarticular osteoid osteoma (OO), expressions of cyclooxygenase-2 (COX-2) protein and its messenger ribonucleic acid were investigated both in the nidus and the synovial tissue using immunohistochemical and reverse transcription-polymerase chain reaction analyses. Diffuse and strong COX-2 immunoreactivity was found in osteoblast-like tumor cells in the nidus of all six cases of OO (three of six cases were intraarticular OO associated with synovitis) and one case of osteoblastoma associated with synovitis. Expression of COX-2 messenger ribonucleic acid was demonstrated in one case of OO associated with synovitis, and was higher in the nidus than that in the inflamed synovial tissue. However, there were no significant difference between the nidus and synovium in the expression of cytosolic phospholipase A2, one of the enzymes involved in arachidonic acid metabolism, and inflammatory cytokines such as interleukin-1␤ and tumor necrosis factor alpha. Finally, as there was only one case in which the examinations of gene expression were performed, no definitive overall conclusions could be reached; rather it is suggested that COX-2 expressed primarily by osteoblasts in the nidus of intraarticular OO may play a role in activating the pathway of arachidonic acid metabolism, resulting in synovitis of the involved joint.

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Section: Discussionsupporting

confidence: 85%

mentioning

confidence: 87%

Intraarticular Osteoid Osteoma Associated with Synovitis: A Possible Role of Cyclooxygenase-2 Expression by Osteoblasts in the Nidus

Kawaguchi

Sato

Hasegawa³

et al. 2000

Modern Pathology

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“…2,31 Juxtanidal marrow oedema is variable; a more pronounced marrow reaction may occur in younger patients. 32 The subtle radiographic appearance combined with the non-specific clinical presentation of intra-articular osteoid osteomas often leads to a delayed diagnosis. 23,33,34 Patients have been reported to have had symptoms for 8 -43 months before the osteoid osteoma is found.…”

Section: Figure 2: Osteoid Osteoma Of the Right Femoral Neck (A) It mentioning

confidence: 99%

Radiofrequency Ablation of Intra-articular Osteoid Osteoma of the Hip

et al. 2006

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Diagnosis and treatment of intra-articular osteoid osteoma is challenging. We present 16 patients with intra-articular osteoid osteomas of the hip treated with percutaneous radiofrequency ablation. Eight osteoid osteomas were located in the femoral head, six in the femoral neck, and two in the acetabulum. Three of the 16 patients had had an incorrect previous diagnosis. Percutaneous radiofrequency ablation was a clinical and technical success in all 16 patients. Within the first 24 h after the procedure, pain improved in all patients. Five patients had pain relief within the first 3 days after the procedure, nine patients within the first week and two patients within 2 weeks. Residual or recurrent symptoms were not reported by the last follow-up. At the 12-month follow-up, computed tomography and magnetic resonance imaging showed complete ossification and bone regeneration at the site of the lesion in three patients, partial ossification in six patients and no changes in seven patients. Computed tomography-guided percutaneous radiofrequency ablation is a simple, minimally invasive, safe and effective method for the treatment of most intra-articular osteoid osteomas.

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“…CT scan is the gold standard for diagnosis; it can clearly identify the nidus, its extension, and is very helpful in differential diagnosis [12]. The use of MRI is controversial since it often fails to identify the nidus, and because of intramedullary oedema it can lead to misdiagnosis (other aggressive or malignant tumors, osteonecrosis or stress fractures) [13,14]. Differential diagnoses include: osteoblastoma, stress fracture, abscess, intracortical osteosarcoma, enostosis [15].…”

Section: Introductionmentioning

confidence: 99%

Osteoid Osteoma of the Distal Fibula: a Case Report of a Very Rare Location Treatment

Santini¹,

Merendi²,

Rocchi³

2017

J Bone Res

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Osteoid Osteoma (OO) is a very common small benign osteoblastic tumor. It represents 10% of all bone benign lesions, and is usually localized to the proximal metadiaphysis of the femur. We report the case of an OO localized in the distal inner metadiaphysis of the fibula. To our knowledge this is the first report in literature. We performed enbloc resection because of the deep localization of the lesion, which was not reachable by minimally invasive procedures. At 6 months follow-up bone stock reconstitution was observed, and no relapse occurred at 1 year. Plain X-rays are generally sufficient to make a diagnosis. When radiological findings are not suggestive, computed tomography and bone scan represent second level examinations. Minimally invasive procedures represent a promising and valuable treatment, but open surgery shall be still taken in account when the location is not easy to reach and/or it is in proximity to neurovascular structures.

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Osteoid osteomas of the femoral neck: report of four cases evaluated with isotopic bone scanning, CT, and MR imaging.

Cited by 88 publications

References 0 publications

Intraarticular Osteoid Osteoma Associated with Synovitis: A Possible Role of Cyclooxygenase-2 Expression by Osteoblasts in the Nidus

Intraarticular Osteoid Osteoma Associated with Synovitis: A Possible Role of Cyclooxygenase-2 Expression by Osteoblasts in the Nidus

Radiofrequency Ablation of Intra-articular Osteoid Osteoma of the Hip

Osteoid Osteoma of the Distal Fibula: a Case Report of a Very Rare Location Treatment

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