Osteogenic sarcoma of the jaws: factors influencing prognosis

Osteosarcomas of flat bones in adolescents and adults

“…The most common failure sites were the craniofacial region and the pelvis (50% and 6%, respectively), as stated in other reports. 8,19,21,[27][28][29] To achieve adequate local control, 5 of the 10 patients with incomplete surgical resection received additional, external, high energy RT. In patients with of unresectable or incompletely resectable tumors, external RT should be used alone or in combination with surgery to achieve adequate local control.…”

Chondroblastic osteosarcoma of maxilla: a case report and review of literature

“…The common presenting feature is a rapidly growing swelling with localized pain [4]. August et al [5] in a study of 30 patients with OSJ reported that the most common presenting symptom was swelling without pain. Other signs and symptoms include displacement and loosening of teeth, paresthesia, epistaxis and nasal obstruction.…”

“…The differences in protocol make it difficult to draw conclusions about their efficacy. August et al [5] reported 30 patients with OSJ treated with combinations of surgery, radiation therapy and chemotherapy. Factors associated with statistically significant poorer prognosis include neurosensory deficit as the presenting symptom, increasing age of patients and surgical margins of less than 5 mm.…”

“…The picture was suggestive of a chondroblastic variant of osteosarcoma. As extensively [1,11] 80% [1] Distal femoral metaphysis proximal tibia and humeral metaphysis [1] Lungs, bones and kidneys [1] Distant metastasis [1] Surgery + adjuvant chemotherapy [15] Related to growth spurt [11] Painful swelling [1] Rare [1] Positive [11] 3rd/4th decade [11,14] 18% [2,14] Maxilla: anterior alveolus and antrum Mandible: Body, symphysis and ascending ramus [4,6] Lung brain [2,14] Locoregional recurrence [2,14] Radical Surgery-(main stay) +/-adjuvant chemotherapy [17] (developed for OSL) Not related to growth spurt [11] Painless swelling-first sign [5] Paresthesia present [5] Negative [11] Features…”

Osteosarcoma of the mandible in an aged person

“…In general, these finding were common in the literature,(l-ll, 13-33) but the higher alkaline phosphatase value was not and was found in approximately one-third of the cases. ( 15,20,(26)(27)(28) The tumor was in the mandibular body and in the common region.…”