Osteogenic and long-term antibacterial properties of Sr/Ag-containing TiO2 microporous coating in vitro and in vivo

Wang, Huan; Zheng, Tian‐Xia; Yang, Nuo‐Ya; Li, Ying; Sun, Hong; Dong, Wei; Feng, Lifang; Deng, Jiu-Peng; Qi, Mengchun

doi:10.1039/d2tb01658c

Cited by 3 publications

(1 citation statement)

References 64 publications

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“…Silver is one of the trace elements present in human tissues and has been utilized for thousands of years as a natural antibacterial material due to its extensive antibacterial spectrum and reduced propensity for generating resistance. In recent times, silver nanoparticles (AgNPs) have garnered significant interest as a classical antibacterial agent in the realm of antibacterial activity ( Zhang Y. Y. et al, 2021 ; Wang H. et al, 2023 ; Wang Y. R. et al, 2023 ; Maj et al, 2023 ). The appeal of AgNPs can be attributed to various factors.…”

Section: Manuscript Formattingmentioning

confidence: 99%

Advancements in incorporating metal ions onto the surface of biomedical titanium and its alloys via micro-arc oxidation: a research review

Zhang,

Zhou,

2024

Front. Chem.

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The incorporation of biologically active metallic elements into nano/micron-scale coatings through micro-arc oxidation (MAO) shows significant potential in enhancing the biological characteristics and functionality of titanium-based materials. By introducing diverse metal ions onto titanium implant surfaces, not only can their antibacterial, anti-inflammatory and corrosion resistance properties be heightened, but it also promotes vascular growth and facilitates the formation of new bone tissue. This review provides a thorough examination of recent advancements in this field, covering the characteristics of commonly used metal ions and their associated preparation parameters. It also highlights the diverse applications of specific metal ions in enhancing osteogenesis, angiogenesis, antibacterial efficacy, anti-inflammatory and corrosion resistance properties of titanium implants. Furthermore, the review discusses challenges faced and future prospects in this promising area of research. In conclusion, the synergistic approach of micro-arc oxidation and metal ion doping demonstrates substantial promise in advancing the effectiveness of biomedical titanium and its alloys, promising improved outcomes in medical implant applications.

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Section: Manuscript Formattingmentioning

confidence: 99%

Advancements in incorporating metal ions onto the surface of biomedical titanium and its alloys via micro-arc oxidation: a research review

Zhang,

Zhou,

2024

Front. Chem.

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Preparation and mechanical and biological performance of the Sr-containing microarc oxidation layer on titanium implants

Liu

Kang

et al. 2023

Surface and Coatings Technology

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Review of microarc oxidation of titanium implant

Yang,

Meng,

Qian

et al. 2023

Journal of Vacuum Science &Amp; Technology B

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Titanium and titanium alloys are the most commonly used implant materials, but they are biologically inert. These materials lack rapid osseointegration and resistance to bacterial infections, problems that remain unsolved. The preparation of titanium dioxide coatings by microarc oxidation improves both the biocompatibility of titanium-based materials and their resistance to corrosion during long-term presence in the body. This paper discusses and summarizes the mechanisms of microarc oxidation and some classical models that need to be developed to provide a better understanding and guidance for future research. Subsequently, the effects of electrolyte type, additives, and surface modification of the microarc oxidized coating on the coating morphology were analyzed in detail. In addition, biological applications of microarc oxidation coatings are analyzed, including antimicrobial properties, osseointegration, hydrophilicity, corrosion resistance, and wear resistance.

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Osteogenic and long-term antibacterial properties of Sr/Ag-containing TiO₂ microporous coating in vitro and in vivo

Abstract: Bacterial infection and poor osseointegration are two critical issues that need to be solved for long-term use of titanium implants.

Cited by 3 publications

References 64 publications

Advancements in incorporating metal ions onto the surface of biomedical titanium and its alloys via micro-arc oxidation: a research review

Advancements in incorporating metal ions onto the surface of biomedical titanium and its alloys via micro-arc oxidation: a research review

Preparation and mechanical and biological performance of the Sr-containing microarc oxidation layer on titanium implants

Review of microarc oxidation of titanium implant

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