Osteoblast adherence and resorption activity of isolated osteoclasts on calcium sulphate hemihydrate

Sidqui, M.; Collin, Pascal; Vitté, C.; Forest, Nadine

doi:10.1016/0142-9612(95)91048-4

Cited by 141 publications

(71 citation statements)

References 25 publications

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“…CS has three phases with various hydration levels; CaSO4·2H2O (gypsum/CSHH), CaSO4·0.5H2O (basanite) and CaSO4 (anhydrite) [10]. Figure 7 shows the XRD patters of the starting powder, asprinted sample and sintered sample to compare the initial phase of the material with printed and sintered phases.…”

Section: Discussionmentioning

confidence: 99%

“…However, according to the specific XRD patterns, the powder consisted of a mixture of both gypsum and basanite phases due to nonhomogeneous contact between binder and powder during the 3DP process ( Figure 6b) [10]. Thirdly, 3D printed and sintered powder was examined with XRD spectroscopy.…”

Section: (1)mentioning

confidence: 99%

“…Moreover, it releases calcium ions which may provide an advantage for osteoblast formation [8]. Calcium sulphate hemihydrate (CSHH) was studied by Sidqui et al [10]. It was reported that osteoblastic cells attach on CSHH and osteoclasts resorb the material.…”

Section: Introductionmentioning

confidence: 99%

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The Effect of Heat Treatment on Physical, Chemical and Structural Properties of Calcium Sulfate Based Scaffolds

Oflaz¹,

Dikici²,

Dikici³

2017

SDÜ Fen Bil Enst Der

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3D printed calcium sulfate (CS) is a promising material for on custom bone substitutes. Since it dissolves easily in body fluids, manufactured samples require to being improved to reduce solubility. The main aim of this study was reducing the dissolubility of CS based samples by using sintering and investigating the effect of heat treatment on their physical, chemical and structural properties. To observe the effect of heat treatment on samples, contact angles were measured, X-Ray diffraction analysis (XRD) was performed, and scanning electron microscope (SEM) micrographs were captured before and after the sintering process, and the results were compared. Furthermore, sintered and non-sintered samples were soaked in phosphate buffered saline (PBS) to observe the impact of sintering on the solubility of the material. Also, three different pore sized scaffolds were manufactured to test the limits of the 3D printer for manufacturing of scaffolds with open pores. Sintering process results in a volume reduction and according to SEM results, CS grains were fused together after heat treatment. Although non-sintered CS sample starts to dissolve in high rate and nearly 1/3 of the sample was at the bottom of the glass in a matter of minutes, sintering creates more rigid structure and there were not visible dissolution in PBS at the end of a week. The contact angle of samples cannot be measured, so it can be concluded that 3D printed material showed a super-hydrophilic property. XRD diagram suggested that there is not any new phase created in the printing and sintering processes except related hydrates of CS. As a result of the 3D printing, 500 µm, 750 µm and 1000 µm pore sized scaffolds were manufactured, successfully. However, it was seen that 500 µm pores could not be open by using depowdering after the printing process. Özet: 3 boyutlu yazdırılmış kalsiyum sülfat (KS), kişiye özel kemik uygulamaları için umut verici bir malzemedir. Bununla birlikte bu malzemenin suya olan düşük dayanıklılığı nedeni ile vücut sıvıları içerisinde kolayca çözünebilmektedir ve bu çözünürlüğün azaltılması için malzemenin geliştirilmesine ihtiyaç duyulmaktadır. Bu çalışmanın asıl amacı, sinterleme işlemi ile KS bazlı örneklerin çözünürlüğünü azaltmak ve bu ısıl işlemin malzemenin fiziksel, kimyasal ve yapısal özellikleri üzerine olan etkisini araştırmaktır. Isıl muamelenin örnekler üzerine olan etkisini incelemek amacı ile sinterleme işlemi öncesi ve sonrası örneklere temas açısı, X ışınları kırınımı (XRD) analizleri uygulanmış, örnek yüzeylerinin taramalı elektron mikroskobu (SEM) görüntüleri alınmış ve sonuçlar karşılaştırılmıştır. Ayrıca, sinterleme işleminin malzeme çözünürlüğü üzerine olan etkisini incelemek amacı ile sinterlenmiş ve sinterlenmemiş örneklerin fosfat tamponlu tuz (PBS) içerisindeki çözünürlükleri gözlemlenmiştir. Ayrıca çalışma kapsamında 3 farklı gözenek çapında iskeleler üretilmiş ve 3 boyutlu yazıcının açık gözenekli iskele üretmedeki limitleri belirlenmiştir. Sinterleme işlemi örneklerin hacmen azalmasına n...

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Section: Discussionmentioning

confidence: 99%

Section: (1)mentioning

confidence: 99%

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The Effect of Heat Treatment on Physical, Chemical and Structural Properties of Calcium Sulfate Based Scaffolds

Oflaz¹,

Dikici²,

Dikici³

2017

SDÜ Fen Bil Enst Der

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“…The advantages of calcium sulfate include its biodegradability, predicable elution properties, osteconductivity, and ability to fill dead space [9]. Recent studies have shown that osteoblasts attach to and absorb calcium sulfate [10]. It provides an osteoconductive environment for vascular ingrowth.…”

Section: Discussionmentioning

confidence: 99%

A Case Report on the Treatment of Metcillin-Resistant Staphylococcus Aureus (Mrsa) Infected Tibial Internal Fixation with Calcium

Pillai¹

2015

Orthop Muscular Syst

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The formation of biofilm is one of the main contributing factors for unsuccessful treatment of osteomyelitis. It is formed through bacterial adhesion to the fragments of dead bone. Poor perfusion or devascularization of an infected bone with changes in local pH further limits the diffusion of parenteral antibiotics.Calcium Sulfate , a biocompatible and completely absorbable local carrier for antibiotics, has shown promising results in treating osteomyelitis. It is associated with less systemic effects and compliance issues when compared with conventional treatment of surgical debridement and prolonged systemic antibiotics.

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“…16 Additionally, calcium sulfate scaffolds serve as an excellent site of adherence for osteoblasts 106 and cause no appreciable inflammation on implantation.…”

Section: Calcium Sulfate Scaffoldsmentioning

confidence: 99%

Cranial bone defects: current and future strategies

Szpalski¹,

Barr²,

Wetterau³

et al. 2010

FOC

177

118

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Bony defects in the craniomaxillofacial skeleton remain a major and challenging health concern. Surgeons have been trying for centuries to restore functionality and aesthetic appearance using autografts, allografts, and even xenografts without entirely satisfactory results. As a result, physicians, scientists, and engineers have been trying for the past few decades to develop new techniques to improve bone growth and bone healing. In this review, the authors summarize the advantages and limitations of current animal models; describe current materials used as scaffolds, cell-based, and protein-based therapies; and lastly highlight areas for future investigation. The purpose of this review is to highlight the major scaffold-, cell-, and protein-based preclinical tools that are currently being developed to repair cranial defects.

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Osteoblast adherence and resorption activity of isolated osteoclasts on calcium sulphate hemihydrate

Cited by 141 publications

References 25 publications

The Effect of Heat Treatment on Physical, Chemical and Structural Properties of Calcium Sulfate Based Scaffolds

The Effect of Heat Treatment on Physical, Chemical and Structural Properties of Calcium Sulfate Based Scaffolds

A Case Report on the Treatment of Metcillin-Resistant Staphylococcus Aureus (Mrsa) Infected Tibial Internal Fixation with Calcium

Cranial bone defects: current and future strategies

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