Osteoarthritis is not a disease, but rather an accumulation of predisposing factors. A systematic review

Gherghel, Robert; Iordan, Daniel Andrei; Mocanu, Mircea-Dan; Onu, Ana; Onu, Ilie

doi:10.12680/balneo.2021.441

Cited by 7 publications

(2 citation statements)

References 47 publications

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“…Some authors suggest that OA is not a disease but a combination of predisposing factors such as the onset of acute inflammation with the perpetuation of mechanisms that maintain a lowgrade chronic inflammation (Musumeci et al, 2015). This chronic inflammation, over time, will develop a destructive effect on articular cartilage, that maintains a vicious circle: inflammation → enzyme production → chondrolysis → inflammation (Gherghel et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

The Endocannabinoid System a Turning Point in Optimizing Physiotherapy Procedures in Knee Osteoarthritis

Onu,

Buculei,

Ionescu

et al. 2023

BRAIN

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Introduction: Knee Osteoarthritis (KOA) is characterized by wear, tear, and it's a slowly progressive loss of cartilage, that becomes finally disabling. KOA is one of the most analyzed diseases by many medical specialties such as rheumatology, orthopedics, rehabilitation medicine, and physiotherapy. Major symptoms of KOA such as pain, dysfunction, and chronic low-grade inflammation will decrease the quality of life and eventually lead to locomotor disability. Since there are no effective ways to limit KOA progression, involvement of the endocannabinoid system (ECS) may be a non-pharmacological therapeutic alternative in the management of this disease. This study debate aspects of ways to modulate the ECS in KOA, using physiotherapeutic (PT) means such as TENS electroanalgesia, LASER biostimulation, and physical exercises with analgesic effects. Materials and Methods: In the study, we included 82 sources, with the following keywords in the title: knee osteoarthritis, cannabidiol, endocannabinoid, inflammatory pain, analgesia, neuropathic pain, physiotherapy, electrotherapy, and LASER. To perform this review, we searched for the most relevant articles in the field of medicine and physiotherapy in 7 international databases applying inclusion and exclusion criteria. Results: The application of TENS currents in certain doses and frequencies together with LASER biostimulation stimulates the production of endocannabinoids thus controlling pain, and stimulating the ECS. Physical exercise has an antioxidant, and anti-inflammatory role and stimulates the release of endogenous opioids. Conclusions: The results obtained from this meta-analysis may contribute to paradigm shifts in clinical practice related to the treatment of pain by PT. TENS, LASER, and physical exercise are effective clinical tool that limits chronic inflammation and pain by involving the ECS. More studies are needed to understand endocannabinoid system involvements in KOA, and that will inspire medical doctors and physiotherapists to improve long-term treatment strategies.

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Section: Introductionmentioning

confidence: 99%

The Endocannabinoid System a Turning Point in Optimizing Physiotherapy Procedures in Knee Osteoarthritis

Onu,

Buculei,

Ionescu

et al. 2023

BRAIN

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“…In addition, progressive injury and loss of articular cartilage cause deformation of the femur and tibia and contracture of the surrounding soft tissues, such as muscles and ligaments, resulting in limited range of motion and muscle weakness in the knee joint. Such pain, limited range of motion, and muscle weakness lead to ADL impairment [2,3]. If the knee OA is resistant to conservative treatments, surgical treatment is performed.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Sit-to-Stand Movement Focusing on Kinematics, Kinetics, and Muscle Activity after Modern Total Knee Arthroplasty

Hyodo,

Kanamori,

Kadone

et al. 2023

Applied Sciences

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The sit-to-stand (STS) movement is important in improving satisfaction after total knee arthroplasty (TKA). Reports on motion analysis using a combination of motion capture systems, force plates, and surface electromyography after TKA are limited. We aimed to compare the STS movement of patients aged over 60 who underwent modern and conventional TKA with more than 6 months of postoperative follow-up. Ten patients underwent surgery with a modern implant (Group I: Smith and Nephew JOURNEY II, Memphis, TN, USA), and ten with a conventional implant (Group II: Smith and Nephew LEGION, Memphis, TN, USA). STS movement kinematics and kinetic data were measured by synchronising a motion capture system with a force plate. Surface electromyography was used to measure the muscle activity. STS time was shorter in Group I than in Group II. Maximum knee-extension angular velocity and maximum knee-extension moment were greater in Group I than in Group II. Electromyography revealed that Group I tended to have less activity in the quadriceps femoris than Group II. Group II had a greater hip-extension moment and vertical ground reaction force, and the hip joint seemed to compensate for knee function. Group I possibly used the quadriceps muscle more effectively, due to the implant shape.

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The effect of motion games on improving the psychomotor and intellectual performance of children with autism spectrum disorder and intellectual disabilities

Mocanu

UDREA

2021

Balneo and PRM Research Journal

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Introduction. Depressive states and anxiety are common symptoms of children with autism spectrum disorder (ASD). The persons with intellectual disabilities show problems related to the development of basic motor skills, having learning problems compared to normal ones, imbalances between the processes of arousal and inhibition, limited motor ability, difficult understanding of language and motor tasks, difficult concentration, mechanical assimilation etc. Objectives. The study analyzes the effectiveness of structures and motion games, applied in specific activities for children with intellectual disabilities (ID) and autism spectrum disorders (ASD). Material and Methods. The research involved an experimental group of 5 children with one of these disabilities or their combination (age 10-11 years), included in a training process at the Ion Teodorescu Special Vocational School in Slobozia / Ialomița / Romania and comparing their results with a control group (6 normal children, with an average age of 10 years), between 20.09.2020-10.03.2021. The assessment of the level of psychomotor and intellectual development was made by the Cutout Test, the Cohs Cube Test (light task configurations) and an Attention Flexibility Test (movement to the corners of the room/field depending on the assigned color, counting successful attempts and mistakes). Results and discussion. The obtained results confirm the working hypothesis, so the use of the structures and games proposed in the program contributes to a significant improvement of the psychomotor and intellectual performances of students with intellectual disabilities and autism spectrum. Conclusion. espite all these improvements, they cannot approach or equal the reference values of children without problems, falling into the same age category. Keywords: psychomotor skills, adapted physical activities, recovery, children, learning disabilities,

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Osteoarthritis is not a disease, but rather an accumulation of predisposing factors. A systematic review

Cited by 7 publications

References 47 publications

The Endocannabinoid System a Turning Point in Optimizing Physiotherapy Procedures in Knee Osteoarthritis

The Endocannabinoid System a Turning Point in Optimizing Physiotherapy Procedures in Knee Osteoarthritis

Evaluation of Sit-to-Stand Movement Focusing on Kinematics, Kinetics, and Muscle Activity after Modern Total Knee Arthroplasty

The effect of motion games on improving the psychomotor and intellectual performance of children with autism spectrum disorder and intellectual disabilities

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