Osseous Gaucher's Disease in Early Childhood

Harrison, William; Louis, Herbert J.

doi:10.1001/jama.1964.03060260025005

JAMA

1964

DOI: 10.1001/jama.1964.03060260025005

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Osseous Gaucher's Disease in Early Childhood

William Harrison¹,

Herbert J. Louis²

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1966

1986

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Cited by 3 publications

References 12 publications

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Femoral neck fractures complicating gaucher disease in children

Goldman

Jacobs

1984

Skeletal Radiol

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In normal children, fractures of the femoral neck are uncommon and accompany severe trauma and multiple injuries elsewhere in the skeleton [16, 17]. In children with Gaucher disease, a rare hereditary disorder of lipid metabolism, midcervical or basicervical fractures can occur with minor or no trauma and without other injury to the skeleton. Three children with Gaucher disease who developed pathologic fractures of the femoral neck are described. In all three, the fractures occurred between five and nine years of age, and the fracture lines passed through areas of abnormal bone characterized by poorly defined patches of increased and decreased density and cortical thinning along the medial femoral necks. In the affected hips, there was no evidence of avascular necrosis of the femoral heads at the time of injury. One child's fracture was preceded by multiple bone "crises" localized to the proximal femora.

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Femoral neck fractures complicating gaucher disease in children

Goldman

Jacobs

1984

Skeletal Radiol

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Solitary bone lesions in children

Taybi

1966

Seminars in Roentgenology

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Skeletal manifestations of Gaucher's disease

Pastakia¹,

Brower²,

Chang³

et al. 1986

Seminars in Roentgenology

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Osseous Gaucher's Disease in Early Childhood

Cited by 3 publications

References 12 publications

Femoral neck fractures complicating gaucher disease in children

Femoral neck fractures complicating gaucher disease in children

Solitary bone lesions in children

Skeletal manifestations of Gaucher's disease

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