Osseointegration of Osseotite^® and machined titanium implants in autogenous bone graft. A histologic and histomorphometric study in dogs

Abstract

It has been shown that a roughened implant surface results in a higher percentage of bone to implant contact (%BIC) than a machined one. A modified implant surface using a dual thermo-acid etching process (Osseotite) has been introduced and evaluated clinically, mechanically and histologically. The aim of the present study was the histological evaluation of the %BIC between the Osseotite or machined surfaces and the autogenous bone graft. Twenty-two custom-made split-type 10-mm-long implants having two opposing surfaces (Osseotite and machined) were placed between the cranial and caudal dorsal iliac spine at the iliac wing of two adult mongrel dogs. An artificial bone defect was created leaving a 2 mm empty space around the coronal 5 mm of the implants, while the apical 5 mm was stabilized in the existing basal bone. The defects around the implants were filled with particulate autogenous bone graft, covered by an Osseoquest membrane, and left to heal for 5 months. All inserted implants showed a complete integration in the bone tissue. It was found that the resulting %BIC at the Osseotite surface was significantly higher than at the machined one in both regenerated (46.44+/-15.81% vs. 28.59+/-12.04%) and basal bone areas (32.32+/-15.09% vs. 17.25+/-7.40%). The findings of this study imply that the use of autogenous bone graft resulted in significantly higher %BIC values in the regenerated area than in the basal bone area itself, for both implant surfaces.

Peri‐implant bone formation and implant integration strength of peptide‐modified p(AAM‐co‐EG/AAC) interpenetrating polymer network‐coated titanium implants

“…7). This value represents the maximum area of mineralization observed in vitro on various peptide-IPN surfaces, and is similar to the maximum reported BIC for model studies with titanium implants 55 and mesenchymal stem cells injected in the peri-implant region at the time of implantation. 56 This value may represent a maximum for BIC in vivo.…”

Improvement of osseointegration of titanium dental implant surfaces modified with CO ions: a comparative histomorphometric study in beagle dogs

“…VEIS et al 26 reported that the BIC value was 32% for acidetched implants versus 17% for machine-turned implants 5 months after implant placement in the mandible of the dog. WENG et al 27 referred to 62%BIC for acid-etched versus 39%BIC for machineturned implants after 4 months in foxhounds.…”

Soft tissue adaptation to modified titanium surfaces

“…For example, mesh designed titanium implants were shown to promote soft tissue ingrowth in vivo associated with an enhanced ingrowth of blood vessels 30. Perhaps, a different configuration of surface modification is required for soft tissue adherence compared with surface roughness that is able to support bony integration 31. Kim et al28 reported that parallel microgrooved surfaces implanted in rats exhibited greater connective tissue attachment and thinner fibrous capsules than polished surfaces.…”