Oropharyngeal teratomas in newborns: Management and outcome

Abstract

Surgery for these mostly benign tumours is very challenging and requires a multidisciplinary team. Perinatal planning allows appropriate management at birth, decreasing the risk of airway obstruction. Surgery is the mainstay of treatment of teratomas.

Diagnosis and Surgical Management of Congenital Intranasal Teratoma in a Newborn: A Rare Case Report

“…Routine follow-up for recurrence should include physical examination and imaging studies when appropriate [ 26 ]. Periodic measurements of serum alpha-fetoprotein (AFP) levels may also be performed, as teratoma recurrences have been detected by elevations of AFP levels after resection [ 27 , 28 ].…”

Proboscis lateralis: A case report of a rare giant craniofacial teratoma in an infant

“…The theory is that most craniofacial teratomas lead to obstructions of the oropharyngeal tract; therefore, the fetus is unable to swallow the amniotic fluid and subsequently develops polyhydramnios [ 4 , 5 ]. Furthermore, a few case studies have suggested that calcifications in the head and neck region of newborn babies could indicate the presence of craniofacial teratomas [ 5 ]. Moreover, MRI is a useful modality for delineating the extent of such tumors in facial and cranial soft tissues [ 13 , 14 ].…”

“…It is estimated that such growths account for 2% of all childhood tumors. The incidence of these growths is estimated to be 1:40,000 live births [ 5 ]. There is a slight female predilection.…”

“…There is a slight female predilection. Approximately 30 cases of proboscis lateralis have been recorded in the last 150 years [ 5 ]. Many such cases have resulted in stillbirth or death shortly after birth from severe disease, which is usually associated with other deformities.…”

“…Many such cases have resulted in stillbirth or death shortly after birth from severe disease, which is usually associated with other deformities. The majority of the reported cases have suffered from significant morbidity despite extensive surgical interventions [ 5 ]. Craniofacial teratomas can be diagnosed prenatally using ultrasound [ 6 ].…”