Orofacial tuberculosis: A diagnostic challenge

Issa, Sabah Abdulaziz; Abdulnabi, Hussein Ali; Jameel, Mustafa Emaduldeen

doi:10.1016/j.idcr.2020.e00825

Cited by 6 publications

(11 citation statements)

References 13 publications

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“…The human bacillus has a great predilection for all weight-bearing bony joints of the body. Haematogenous dissemination and trauma are usually considered the major aetiologic factors for TBO of the condyle,[ 1 5 6 ] even though the pathomechanism is multifactorial and the exact aetiology remains unclear.…”

Section: Discussionmentioning

confidence: 99%

“…Tuberculosis (TB) is one of the oldest, daunting microbial infections known to humankind, affecting approximately 20-43% of the world’s population. [ 1 ] The orofacial region accounts for approximately 10% incidence of extrapulmonary TB, usually arising from secondary lymphohematogenous dissemination of acid-fast Mycobacterium tuberculosis . [ 1 ] Orofacial TB primarily affects the tongue, palate, gingiva and floor of the mouth with rare involvement of jaws.…”

Section: Introductionmentioning

confidence: 99%

“…[ 1 ] The orofacial region accounts for approximately 10% incidence of extrapulmonary TB, usually arising from secondary lymphohematogenous dissemination of acid-fast Mycobacterium tuberculosis . [ 1 ] Orofacial TB primarily affects the tongue, palate, gingiva and floor of the mouth with rare involvement of jaws. It can be primary or secondary.…”

Section: Introductionmentioning

confidence: 99%

“…Orofacial tubercular osteomyelitis (TBO) is a rare presentation and poses a diagnostic challenge, with only 3% of TB cases reported in the literature. [ 1 2 ] As the oral cavity is lined by squamous epithelium, it resists the penetration of microbes. The pH of saliva and its contents like anti-microbial enzymes prevents the multiplication and colonisation of the microbes.…”

Section: Introductionmentioning

confidence: 99%

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Primary Tubercular Osteomyelitis Affecting the Mandibular Condyle - A Case Report

Gupta

Jadhav²,

Bhola³

et al. 2022

Annals of Maxillofacial Surgery

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Rationale: Primary orofacial tuberculosis (TB) accounts for <3% of all cases of TB. TB of the mandibular condyle is often misdiagnosed owing to its rarity. Patient Concerns: This report presents a 19-year-old female who presented with a painful swelling over the right preauricular region. The radiographic evaluation suggested a diagnosis of suppurative osteomyelitis of the condyle. Diagnosis: Clinically, the aetiology of the swelling was considered as infective. The histopathological examination of the resected specimen showed tuberculous granuloma and the polymerase chain reaction came positive.This confirms the diagnosis of tubercular osteomyelitis. Mantoux test and sputum acid-fast bacilli were found to be negative. Treatment: The patient was subjected to sequestrectomy with high condylectomy and systemic multidrug antitubercular regimen for 6 months. Outcomes: There was a resolution of infection postoperatively with subsequent regeneration of healthy bone. Take-away Lessons: Early identification and prompt diagnosis is imperative for better treatment outcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Primary Tubercular Osteomyelitis Affecting the Mandibular Condyle - A Case Report

Gupta

Jadhav²,

Bhola³

et al. 2022

Annals of Maxillofacial Surgery

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“…Extra-pulmonary involvement mainly occurs due to endogenous spread of the pathogen from the primary site. The primary form arises from direct inoculation of the infecting pathogens in the susceptible sites in absence of systemic involvement, like in soft tissues of the oral cavity and the jawbone, mostly the mandible, where possible routes of infection are both sites of recent dental extraction, mucosal wounds or lacerations, and systemic hematogenous and/or lymphatic spread [ 7 ]. Clinically, tuberculosis may resemble periodontal or periapical lesions or abscesses with or without intra- or extra-oral draining, or as an impressive ulceration of oral mucosa associated or not to cervical lymphadenopathy [ 6 , 7 , 8 ].…”

Section: Infectious Diseasesmentioning

confidence: 99%

Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

2021

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Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

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