2003
DOI: 10.1002/bjs.4277
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Origin of symptoms in diverticular disease

Abstract: Several theories now exist about the mechanisms underlying the symptoms of diverticular disease. Initial studies suggested that they may be due to alterations in the intracolonic pressure, extrapolating earlier thoughts on the likely pathogenesis of diverticula. It seems more likely, however, that several inter-related processes, such as muscular dysfunction, visceral hypersensitivity and inflammation, are involved in symptom generation.

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Cited by 71 publications
(44 citation statements)
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“…1,16 Since the prevalence of peptic ulcer has declined substantially, perforations have become less common. [20][21][22] For other conditions, such as acute cholecystitis, acute pancreatitis or diverticular disease, 14,29,30 the choices are less clear-cut. Conservative measures are usually used before surgery is considered, unless evidence of perforation or blockage exists.…”
Section: Other Diseases Requiring Surgerymentioning
confidence: 99%
“…1,16 Since the prevalence of peptic ulcer has declined substantially, perforations have become less common. [20][21][22] For other conditions, such as acute cholecystitis, acute pancreatitis or diverticular disease, 14,29,30 the choices are less clear-cut. Conservative measures are usually used before surgery is considered, unless evidence of perforation or blockage exists.…”
Section: Other Diseases Requiring Surgerymentioning
confidence: 99%
“…1,2 The spectrum of clinical features extends from asymptomatic diverticulosis and recurrent courses to symptomatic disease with potentially fatal complications. 3 Within the last 14 years, 4 elective laparoscopy-assisted sigmoid resection has developed into a standard procedure for treating symptomatic diverticular disease. 5 The literature is particularly controversial in discussing the time of surgery after an acute attack of diverticulitis.…”
mentioning
confidence: 99%
“…As mentioned earlier, clinical diagnosis of diverticulitis can lead to misdiagnosis and produce significant sampling bias. In addition, symptomatic uncomplicated diverticulosis or asymptomatic diverticulosis can present with IBS-like symptoms [25][26][27][28][29][30]. However, we found active inflammation in the diverticular sac and confirmed acute diverticulitis by CT scan.…”
Section: Discussionmentioning
confidence: 50%