Systematic reviews of clinical decision tools for acute abdominal pain

Abstract

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Variation in costs of emergency laparotomy following a multicentre national audit

“…However, as well as the classical pathway involving IgE and its highaffinity receptor FcRI, we are just beginning to understand some mast cell activation pathways and effector mechanisms, for example, identification of an alternative pathway mediated by IgG, FccRIII, macrophages and platelet activating factor (PAF), and the previously unsuspected importance of nitric oxide, endothelial nitric oxide synthase, PAF, PI3-K ⁄ Akt signalling, cytokines IL-4 and IL-13, sphingosine-1-phosphate and sphingosine kinases [3][4][5].…”

Emergency surgery: the big three – abdominal aortic aneurysm, laparotomy and hip fracture

“…There is a lack of research providing specific evidence of best practice for emergency laparotomy in the elderly patient [49,50]. Therefore, anaesthetic management is extrapolated from data on younger patients, adjusted for reduced physiological reserve [51], and includes fluid therapy guided by appropriate monitoring aimed towards treating critically ill patients with signs of sepsis.…”

Assessing the strengths and weaknesses of a computer assisted medication review in hospitalized patients

“…To guarantee satisfaction of physicians it is also important that the timing of presenting the notifications to the physicians is accurate, e.g. that the notifications are not presented too late, [13,31,32].…”