Organophosphate pesticide: usage, environmental exposure, health effects, and microbial bioremediation

Mahajan, Rishi; Verma, Shalini; Chandel, Shalini; Chatterjee, Subhankar

doi:10.1016/b978-0-323-85455-9.00013-8

Cited by 9 publications

(4 citation statements)

References 97 publications

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“…Organophosphate pesticides are mainly used as insecticides. They are very toxic to bees, wildlife, and even humans since they inhibit acetylcholinesterase (AChE) in the nervous system [150]; some examples are malathion, methyl parathion, and trichlorfon [149,151]. Urea pesticides are also primarily used as herbicides, affecting the photosynthesis of plants.…”

Section: Pesticidesmentioning

confidence: 99%

Field-Effect Transistor-Based Biosensors for Environmental and Agricultural Monitoring

Elli

Hamed

Petrelli

et al. 2022

Sensors

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The precise monitoring of environmental contaminants and agricultural plant stress factors, respectively responsible for damages to our ecosystems and crop losses, has nowadays become a topic of uttermost importance. This is also highlighted by the recent introduction of the so-called “Sustainable Development Goals” of the United Nations, which aim at reducing pollutants while implementing more sustainable food production practices, leading to a reduced impact on all ecosystems. In this context, the standard methods currently used in these fields represent a sub-optimal solution, being expensive, laboratory-based techniques, and typically requiring trained personnel with high expertise. Recent advances in both biotechnology and material science have led to the emergence of new sensing (and biosensing) technologies, enabling low-cost, precise, and real-time detection. An especially interesting category of biosensors is represented by field-effect transistor-based biosensors (bio-FETs), which enable the possibility of performing in situ, continuous, selective, and sensitive measurements of a wide palette of different parameters of interest. Furthermore, bio-FETs offer the possibility of being fabricated using innovative and sustainable materials, employing various device configurations, each customized for a specific application. In the specific field of environmental and agricultural monitoring, the exploitation of these devices is particularly attractive as it paves the way to early detection and intervention strategies useful to limit, or even completely avoid negative outcomes (such as diseases to animals or ecosystems losses). This review focuses exactly on bio-FETs for environmental and agricultural monitoring, highlighting the recent and most relevant studies. First, bio-FET technology is introduced, followed by a detailed description of the the most commonly employed configurations, the available device fabrication techniques, as well as the specific materials and recognition elements. Then, examples of studies employing bio-FETs for environmental and agricultural monitoring are presented, highlighting in detail advantages and disadvantages of available examples. Finally, in the discussion, the major challenges to be overcome (e.g., short device lifetime, small sensitivity and selectivity in complex media) are critically presented. Despite the current limitations and challenges, this review clearly shows that bio-FETs are extremely promising for new and disruptive innovations in these areas and others.

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Section: Pesticidesmentioning

confidence: 99%

Field-Effect Transistor-Based Biosensors for Environmental and Agricultural Monitoring

Elli

Hamed

Petrelli

et al. 2022

Sensors

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“…In general, they are safer and more ecologically friendly than some older insecticides. For instance, the acute oral toxicity of chlorantraniliprole is much lower than that of chlorpyrifos, with LD50 values of over 5,000 mg/kg (in rats) and over 60 mg/kg (in rats), respectively [27,28]. As a result, diamides use to be one of the most common MOAs used today [6,29].…”

Section: Introductionmentioning

confidence: 99%

Characterization of the inheritance of field-evolved resistance to diamides in the fall armyworm (Spodoptera frugiperda) (Lepidoptera: Noctuidae) population from Puerto Rico

Posos-Parra,

Mota-Sanchez,

Pittendrigh

et al. 2024

PLoS ONE

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The fall armyworm (Spodoptera frugiperda) is one of the most destructive pests of corn. New infestations have been reported in the East Hemisphere, reaching India, China, Malaysia, and Australia, causing severe destruction to corn and other crops. In Puerto Rico, practical resistance to different mode of action compounds has been reported in cornfields. In this study, we characterized the inheritance of resistance to chlorantraniliprole and flubendiamide and identified the possible cross-resistance to cyantraniliprole and cyclaniliprole. The Puerto Rican (PR) strain showed high levels of resistance to flubendiamide (RR50 = 2,762-fold) and chlorantraniliprole (RR50 = 96-fold). The inheritance of resistance showed an autosomal inheritance for chlorantraniliprole and an X-linked inheritance for flubendiamide. The trend of the dominance of resistance demonstrated an incompletely recessive trait for H1 (♂ SUS × ♀ PR) × and an incompletely dominant trait for H2 (♀ SUS × ♂ PR) × for flubendiamide and chlorantraniliprole. The PR strain showed no significant presence of detoxification enzymes (using synergists: PBO, DEF, DEM, and VER) to chlorantraniliprole; however, for flubendiamide the SR = 2.7 (DEM), SR = 3.2 (DEF) and SR = 7.6 (VER) indicated the role of esterases, glutathione S- transferases and ABC transporters in the metabolism of flubendiamide. The PR strain showed high and low cross-resistance to cyantraniliprole (74-fold) and cyclaniliprole (11-fold), respectively. Incomplete recessiveness might lead to the survival of heterozygous individuals when the decay of diamide residue occurs in plant tissues. These results highlight the importance of adopting diverse pest management strategies, including insecticide rotating to manage FAW populations in Puerto Rico and other continents.

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“…OPs are mainly bio-transformed in the liver via CYP450 (phase I) by chemical reactions (oxidative desulfurization), to form highly toxic compounds, such as oxon metabolites. The metabolic process of detoxification consists of reactions (phase II) of dearylation and hydrolysis to convert the oxon into dialkyl phosphates (DAPs), dialkyl thiophosphates (DATPs), and 2-isopropyl-4-methyl-6-hydroxy pyrimidine (IMPH), which are highly soluble metabolites that can be excreted mainly through urinary conjugation reactions [ 7 , 8 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Organophosphate-Pesticide-Mediated Immune Response Modulation in Invertebrates and Vertebrates

Bernal-González

Covantes-Rosales

Camacho-Pérez

et al. 2023

IJMS

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Organophosphate pesticides (OPs) have greatly facilitated food production worldwide, and their use is not limited to agriculture and the control of pests and disease vectors. However, these substances can directly affect the immune response of non-target organisms. In this sense, exposure to OPs can have negative effects on innate and adaptive immunity, promoting deregulation in humoral and cellular processes such as phagocytosis, cytokine expression, antibody production, cell proliferation, and differentiation, which are crucial mechanisms for host defense against external agents. This review focuses on the scientific evidence of exposure to OPs and their toxic effects on the immune system of non-target organisms (invertebrates and vertebrates) from a descriptive perspective of the immuno-toxic mechanisms associated with susceptibility to the development of bacterial, viral, and fungal infectious diseases. During the exhaustive review, we found that there is an important gap in the study of non-target organisms, examples of which are echinoderms and chondrichthyans. It is therefore important to increase the number of studies on other species directly or indirectly affected by Ops, to assess the degree of impact at the individual level and how this affects higher levels, such as populations and ecosystems.

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Organophosphate pesticide: usage, environmental exposure, health effects, and microbial bioremediation

Cited by 9 publications

References 97 publications

Field-Effect Transistor-Based Biosensors for Environmental and Agricultural Monitoring

Field-Effect Transistor-Based Biosensors for Environmental and Agricultural Monitoring

Characterization of the inheritance of field-evolved resistance to diamides in the fall armyworm (Spodoptera frugiperda) (Lepidoptera: Noctuidae) population from Puerto Rico

Organophosphate-Pesticide-Mediated Immune Response Modulation in Invertebrates and Vertebrates

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