Organochlorine exposure and risk of breast cancer

Høyer, Annette Pernille; Grandjean, Philippe; Jørgensen, Torben; Brock, John W.; Hartvig, Helle Bøggild

doi:10.1016/s0140-6736(98)04504-8

Cited by 322 publications

(131 citation statements)

References 17 publications

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“…Epidemiological studies suggest a positive correlation between blood levels of chemicals with estrogenic activity, such as organochlorine pollutants, and breast cancer incidence among women, implying that the growing risk of contracting mammary cancer may be linked to the wide distribution of synthetic xenoestrogens (12,13,(44)(45)(46)(47). On the other hand, beneficial health effects have been attributed to the dietary intake of natural phytoestrogens in food of plant origin (17,18).…”

Section: Discussionmentioning

confidence: 99%

Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells

2005

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Section: Discussionmentioning

confidence: 99%

Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells

2005

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“…The study indicated that women with concentrations of dieldrin in their blood had a 200% increased chance of having breast cancer (164). A follow-up study published in May 2000 (165) indicated that dieldrin also affects women's breast cancer survival rate.…”

Section: Epidemiologymentioning

confidence: 97%

“…Hoyer et al (164) published a study in 1998 of 7,712 Danish women observed over 17 years. The study indicated that women with concentrations of dieldrin in their blood had a 200% increased chance of having breast cancer (164).…”

Section: Epidemiologymentioning

confidence: 99%

Aldrin and dieldrin: a review of research on their production, environmental deposition and fate, bioaccumulation, toxicology, and epidemiology in the United States.

Jorgenson¹

2001

Environ Health Perspect

124

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In the last decade four international agreements have focused on a group of chemical substances known as persistent organic pollutants (POPs). Global agreement on the reduction and eventual elimination of these substances by banning their production and trade is a long-term goal. Negotiations for these agreements have focused on the need to correlate data from scientists working on soil and water sampling and air pollution monitoring. Toxicologists and epidemiologists have focused on wildlife and human health effects and understanding patterns of disease requires better access to these data. In the last 20 years, substantial databases have been created and now are becoming available on the Internet. This review is a detailed examination of 2 of the 12 POPs, aldrin and dieldrin, and how scientific groups identify and measure their effects. It draws on research findings from a variety of environmental monitoring networks in the United States. An overview of the ecologic and health effects of aldrin and dieldrin provides examples of how to streamline some of the programs and improve access to mutually useful scientific data. The research groups are located in many government departments, universities, and private organizations. Identifying databases can provide an "information accelerator" useful to a larger audience and can help build better plant and animal research models across scientific fields.

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“…Organochlorine pesticides include a large number of different chemical substances, and some of these compounds have been linked to diseases, such as breast cancer (Høyer et al, 1998). The use of most of these substances has been banned in the EU and USA since the 1980s.…”

Section: Public Healthmentioning

confidence: 99%

Sustainability of livestock production systems : a comparing conventional and organic livestock husbandry

Wagenberg¹,

Haas²,

Hogeveen³

et al. 2016

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This study analysed peer-reviewed literature comparing conventional and organic livestock production systems on sustainability indicators within the topics of economy, productivity, environment, animal welfare and public health. For many indicators, insufficient data were found to draw any conclusions on a difference. The strong points of both conventional and organic livestock production systems were used to formulate lessons learned for sustainable livestock production systems. As sustainability indicators often interact with other sustainability indicators in opposing directions, sustainable livestock production should be approached as a multi-criteria problem optimising a balanced combination of sustainability indicators in all topics.Deze studie heeft wetenschappelijke literatuur geanalyseerd, die conventionele en biologische dierlijke productiesystemen kwantitatief vergelijkt op duurzaamheidsindicatoren binnen de onderwerpen economie, productiviteit, milieu, dierenwelzijn en volksgezondheid. Voor veel indicatoren zijn onvoldoende gegevens gevonden om conclusies te trekken over een verschil. Gevonden sterke punten van zowel conventionele als biologische systemen zijn gebruikt om lessen te trekken voor duurzame veehouderij. Aangezien duurzaamheidsindicatoren vaak onderling samenhangen in tegenstrijdige richting moet een duurzame veehouderij gezien worden als een multicriteria beslissingsprobleem, waarin een gebalanceerde combinatie van indicatoren uit alle duurzaamheidsonderwerpen moet worden geoptimaliseerd.

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Organochlorine exposure and risk of breast cancer

Cited by 322 publications

References 17 publications

Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells

Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells

Aldrin and dieldrin: a review of research on their production, environmental deposition and fate, bioaccumulation, toxicology, and epidemiology in the United States.

Sustainability of livestock production systems : a comparing conventional and organic livestock husbandry

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