Organization of the visual system in larval lampreys: An HRP study

Miguel, Encarnación de; Rodicio, Marı́a Celina; Anadón, Ramón

doi:10.1002/cne.903020309

Cited by 71 publications

(73 citation statements)

References 38 publications

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“…In lampreys this pathway has been extensively studied in larval, transforming and adult animals [Northcutt and Przybylski, 1973;Kennedy and Rubinson, 1977;Kosareva et al, 1977;Kosareva, 1980;Repérant et al, 1980;Vesselkin et al, 1980Vesselkin et al, , 1984De Miguel et al, 1990]. Our results confirm the existence of two optic tracts that can be easily followed to their end in the superficial layers of the OT.…”

Section: Afferents From the Retinasupporting

confidence: 78%

“…Following application of biocytin in the eye bulb, both retinofugal and retinopetal connections were revealed, as previously reported by using other techniques [Kennedy and Rubinson, 1977;Kosareva, 1980;Repérant et al, 1980Repérant et al, , 1982Vesselkin et al, 1980Vesselkin et al, , 1984Vesselkin et al, , 1996Vesselkin and Repérant, 1985;De Miguel et al, 1990;Rodicio et al, 1995]. Briefly, retinofugal fibers of the optic tract projected mostly to the superficial layers of the contralateral OT (SM and SO) and constituted the lateral and axial optic tracts, whereas the retinopetal cells distributed in the M5 nucleus of Schöber and the mesencephalic reticular area ( fig.…”

Section: Complementary Experimentssupporting

confidence: 49%

“…The presence of collaterals in retinofugal axons coursing to the preoptic area or the infrachiasmatic part of the nucleus of the postoptic commissure, where they can establish synaptic connections, was previously reported in lampreys [De Miguel et al, 1990;Weigle et al, 1996]. However, the possibility of corresponding to collateral fibers projecting through the contralateral optic tract cannot be ruled out.…”

Section: Afferents From the Retinamentioning

confidence: 72%

“…Retinal projections in larval, transforming, and adult lampreys have been the matter of numerous experimental studies [Northcutt and Przybylski, 1973;Kennedy and Rubinson, 1977;Kosareva et al, 1977;Kosareva, 1980;Repérant et al, 1980;Vesselkin et al, 1980Vesselkin et al, , 1984De Miguel et al, 1990]. Data presented by these authors demonstrated the presence of a major contralateral retinal projection to the OT, but also a small ipsilateral projection.…”

Section: Introductionmentioning

confidence: 67%

“…In addition to the OT, the retinofugal tracts also contribute to prethalamic, thalamic and pretectal terminal fields [Kennedy and Rubinson, 1977;Vesselkin et al, 1980;De Miguel et al, 1990]. Three radial layers can be distinguished in these diencephalic regions: a periventricular layer that is densely packed with cell bodies, an intermediate layer with migrated cells, and a superficial layer that mostly contains neuropil and fiber tracts [Pombal and Puelles, 1999].…”

Section: Diencephalic Projectionsmentioning

confidence: 99%

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Afferent Connections of the Optic Tectum in Lampreys: An Experimental Study

Arriba

Pombal²

2006

Brain Behav Evol

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Tectal afferents were studied in adult lampreys of three species (Ichthyomyzon unicuspis, Lampetra fluviatilis, and Petromyzon marinus) following unilateral BDA injections into the optic tectum (OT). In the secondary prosencephalon, neurons projecting to the OT were observed in the pallium, the subhipoccampal lobe, the striatum, the preoptic area and the hypothalamus. Following tectal injections, backfilled diencephalic cells were found bilaterally in: prethalamic eminence, ventral geniculate nucleus, periventricular prethalamic nucleus, periventricular pretectal nucleus, precommissural nucleus, magnocellular and parvocellular nuclei of the posterior commissure and pretectal nucleus; and ipsilaterally in: nucleus of Bellonci, periventricular thalamic nucleus, nucleus of the tuberculum posterior, and the subpretectal tegmentum, as well as in the pineal organ. At midbrain levels, retrogradely labeled cells were seen in the ipsilateral torus semicircularis, the contralateral OT, and bilaterally in the mesencephalic reticular formation and inside the limits of the retinopetal nuclei. In the hindbrain, tectal projecting cells were also bilaterally labeled in the dorsal and lateral isthmic nuclei, the octavolateral area, the sensory nucleus of the descending trigeminal tract, the dorsal column nucleus and the reticular formation. The rostral spinal cord also exhibited a few labeled cells. These results demonstrate a complex pattern of connections in the lamprey OT, most of which have been reported in other vertebrates. Hence, the lamprey OT receives a large number of nonvisual afferents from all major brain areas, and so is involved in information processing from different somatic sensory modalities.

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Section: Afferents From the Retinasupporting

confidence: 78%

Section: Complementary Experimentssupporting

confidence: 49%

Section: Afferents From the Retinamentioning

confidence: 72%

Section: Introductionmentioning

confidence: 67%

Section: Diencephalic Projectionsmentioning

confidence: 99%

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Afferent Connections of the Optic Tectum in Lampreys: An Experimental Study

Arriba

Pombal²

2006

Brain Behav Evol

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Secondary vestibulo-oculomotor projections in larval sea lamprey: Anterior octavomotor nucleus

Pombal

Rodicio

Anadón³

1996

J. Comp. Neurol.

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The ventral octavolateral area of lampreys contains three nuclei: the anterior, intermediate and posterior octavomotor nuclei, formed of large neurons that are contacted by thick primary vestibular fibres. We used horseradish peroxidase (HRP) or fluorescein-dextran-amine (FDA) labelling to study the projections of the anterior octavomotor nucleus (AON) in the larval sea lamprey, Petromyzon marinus. The tracers were injected either in the AON, the oculomotor nucleus or the rostralmost spinal cord. HRP injection in the AON labelled thick axons that coursed to the basal mesencephalic tegmentum, where most decussate and project to the oculomotor nucleus and the third Müller cell. Electron microscopy confirmed that AON axons contact with the contralateral third Müller cell and with oculomotor neurons. Some AON axons run in the mesencephalic tegmentum and the ventral diencephalon. An AON axon was observed to run close to the axon of the contralateral third Müller cell, establishing what appeared to be en passant contacts. HRP injection in the AON also revealed commissural fibres projecting to the contralateral octavolateral area. HRP or FDA injections in the oculomotor nucleus labelled both large and small neurons of the AON, mostly contralateral to the injection site, as well as of cells in the intermediate octavomotor nucleus, mainly ipsilateral. HRP injection in the AON or in the rostral spinal cord did not reveal any projections from the AON to the spinal cord. Our results indicate that the pattern of octavo-oculomotor connections in the lamprey is different from that observed in other vertebrates.

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Afferents of the lamprey striatum with special reference to the dopaminergic system: A combined tracing and immunohistochemical study

1997

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The origin of afferents to the striatum in lamprey (Lampetra fluviatilis) was studied by using fluorescein-coupled dextran-amines (FDA). Injection of FDA into the striatum retrogradely labeled several cell populations in the forebrain and the rostral rhombencephalon. No retrograde labeled cells were seen in the mesencephalon. A dopamine-specific antiserum was used to determined the distribution of dopaminergic perikarya and fibers. Many dopamine-immunoreactive (DA-ir) fibers were present throughout the brain, but the highest density of labeled fibers was in the mediobasal prosencephalon, especially in the striatum, the lateral hypothalamic area, and the neurohypophysis. Most DA-ir cells were located in the mediobasal diencephalon (preoptic region, nucleus commissurae postopticae, hypothalamus, and nucleus tuberculi posterioris). In the mesencephalon, only a few immunopositive cells were observed in the tectum opticum. In the rhombencephalon, DA-ir cells were observed in the isthmic region, dorsally to the descending trigeminal tract, and caudally to the posterior rhombencephalic reticular nucleus. The rostralmost spinal cord received many descending DA-ir fibers from the brainstem. Along the spinal cord, DA-ir neurons were also found, some of which projected to the medioventral surface, forming a prominent plexus. On the basis of double-labeling experiments, it is shown that the dopaminergic input to the striatum originates from the nucleus tuberculi posterioris. Thus, the striatum receives inputs from different structures, including a strong dopaminergic innervation from the diencephalon. Much of the dopaminergic system in Lampetra fluviatilis is basically similar to that seen in some teleosts, but it presents differences with other anamniote (elasmobranch) as well as amniote groups.

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Organization of the visual system in larval lampreys: An HRP study

Cited by 71 publications

References 38 publications

Afferent Connections of the Optic Tectum in Lampreys: An Experimental Study

Afferent Connections of the Optic Tectum in Lampreys: An Experimental Study

Secondary vestibulo-oculomotor projections in larval sea lamprey: Anterior octavomotor nucleus

Afferents of the lamprey striatum with special reference to the dopaminergic system: A combined tracing and immunohistochemical study

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