Organ-to-organ and seasonal variations of alkaloids from Crinum moorei

Phytochemistry and Pharmacology of the Family Amaryllidaceae: An Overview of Research at RCPGD

“…Crinine 2 and its derivatives buphanisine 45 and powelline 27 were found in higher concentrations in the bulb. 40 Seasonal and year-to-year variations in alkaloid content of C. moorei were also observed. Bulbs had the highest levels of lycorine 3, crinine 2, and undulatine 26 in winter during the first year of the study, while bulbs had the highest concentrations of lycorine 3 and crinine 2 in summer and had the lowest concentration of undulatine 26 in winter.…”

“…Bulbs had the highest levels of lycorine 3, crinine 2, and undulatine 26 in winter during the first year of the study, while bulbs had the highest concentrations of lycorine 3 and crinine 2 in summer and had the lowest concentration of undulatine 26 in winter. 40 The high variability of alkaloid content in these species was due to high variation among plants of the same species collected in the same season. This variability is attributed to the fact that most members of the family Amaryllidaceae are self-sterile and seeds are seldom produced after self-fertilization.…”

“…17 Therefore, a number of studies on ontogenic variations of Amaryllidaceae alkaloids have also been conducted on some of the South African members of the family. [38][39][40] In a study investigating the seasonal and plant parts variation of C. macowanii over 2 consecutive years, bulbs were found to have high alkaloid content compared to leaves, roots, and flowering stalks. Crinine 2 and lycorine 3 were the major alkaloids detected in C. macowanii.…”