Orchidopexy trends in the paediatric population of Victoria, 1999-2006

Bonney, Tamara; Southwell, Bridget R.; Donnath, Susan; Newgreen, Donald F.; Hutson, John M.

doi:10.1016/j.jpedsurg.2008.10.099

Cited by 22 publications

(20 citation statements)

References 21 publications

(20 reference statements)

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“…In the State of Victoria, Australia, there has been a true decline in the number of orchidopexy operations done in children between 1999 and 2006. This may represent a true decline in the incidence of disease, a failure of diagnosis, or a failure of management [118]. Therefore, with an overall worldwide prevalence of undescended testes within the first years of life of 1% to 2%, the orchidopexy rates around 2.4% to 3.8% fit well with the figure that half the orchidopexies in childhood are performed on ascending or severely retractile testes.…”

Section: Epidemiologymentioning

confidence: 55%

What is new in cryptorchidism and hypospadias—a critical review on the testicular dysgenesis hypothesis

Thorup

McLachlan

Cortes

et al. 2010

Journal of Pediatric Surgery

162

102

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Section: Epidemiologymentioning

confidence: 55%

What is new in cryptorchidism and hypospadias—a critical review on the testicular dysgenesis hypothesis

Thorup

McLachlan

Cortes

et al. 2010

Journal of Pediatric Surgery

162

102

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“…2,31–33 This variation in temporal observations – as well as the wide variation in cryptorchidism occurrence as reported in the literature (1–9%) – is at least partially an indication of the wide geographical variation that has been observed between countries. For example, boys born in Denmark are more than four times as likely to have cryptorchidism as boys born in Finland, while boys born in Lithuania have an intermediate prevalence between Denmark and Finland.…”

Section: Introductionmentioning

confidence: 70%

Risk factors for cryptorchidism

et al. 2017

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The condition known as cryptorchidism – undescended testis – is one of the most common congenital abnormalities found among males, and is one of the few known risk factors for testicular cancer (TC). Like testicular cancer, the key exposures in the occurrence of cryptorchidism remain elusive. Testicular descent is thought to occur during two hormonally-controlled phases – between 8–15 weeks and 25–35 weeks gestation – and while it is clear that a failure of testes to descend permanently is likely due to disruptions to one or both of these phases, the cause(s) and mechanism(s) of such disruption are still unclear. In this manuscript, we review the broad range of putative risk factors that have been evaluated in relation to the development of cryptorchidism to date, discuss their plausibility, and make suggestions regarding further approaches to understand aetiology. There are few exposures for which there is consistent evidence of an association with cryptorchidism; and in those cases where evidence appears unequivocal – for example, the relationship between cryptorchidism and gestational measures such as low birth weight – the measured exposure is likely to be a surrogate for the true causal exposure. The relative importance of each risk factor may vary considerably between mother/son pairs depending on an array of genetic, maternal, placental and foetal factors – all of which could vary between regions.

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“…17 We found a decrease in prevalence of treated UDT over the past decade, which appears consistent with worldwide reported trends in Germany, New Zealand, Norway, and Russia 18 and the Australian states of Victoria and Western Australia. 19,20 To our knowledge, this is the first population-based study (n = 4980, 65 sites) reporting rates for testicular atrophy (1.8%), torsion (1.2%), and subsequent outcomes of orchidopexy, with 9% of patients requiring revision surgery and a rate of testicular atrophy at second surgery of 3.6%. To date, the only other published multicenter study (10 sites, n = 281 patients) reported overall 7.2% and 6.1% rates of failure and atrophy, respectively, in patients undergoing laparoscopic orchidopexy.…”

Section: Discussionmentioning

confidence: 90%