2015
DOI: 10.11604/pamj.2015.20.297.6135
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Oral verrucous carcinoma complicating a repetitive injury by the dental prosthesis: a case report

Abstract: Verrucous carcinoma (VC) is an unusual, well differentiated, and low-grade type of squamous cell carcinoma, characterized by benign histology and cytology but markedly invasive clinical behavior. They have a predilection for squamous mucosae, particularly those of the head and neck region. Many factors have been associated with its pathogenesis, including the presence of previous skin lesions; VC arising from a prosthesis injury is rare. Here we reported a case of VC of oral cavity a particularly very aggressi… Show more

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Cited by 5 publications
(8 citation statements)
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“…For instance, the differentiation of OVC from OSCC is important regarding their different molecular mechanisms and prognoses. However, it is currently difficult to differentiate them by simply observing clinical and pathological features because OVC has similar biological behavior to OSCC, including tendency to local invasion, insidious lymph node metastasis and occurrence of malignant lesions (10). These similarities usually cause clinical misdiagnosis and mistreatment (11).…”
Section: Introductionmentioning
confidence: 99%
“…For instance, the differentiation of OVC from OSCC is important regarding their different molecular mechanisms and prognoses. However, it is currently difficult to differentiate them by simply observing clinical and pathological features because OVC has similar biological behavior to OSCC, including tendency to local invasion, insidious lymph node metastasis and occurrence of malignant lesions (10). These similarities usually cause clinical misdiagnosis and mistreatment (11).…”
Section: Introductionmentioning
confidence: 99%
“…Alguns autores (ZANINE et al, 2004;RAHALI et al, 2015;NEVILLE et al, 2016;FRANKLYN et al, 2017) referem que a lesão do CV ocorre frequentemente no local de colocação crônica do tabaco, podendo acometer o fundo de vestíbulo, língua, palato duro, mucosa jugal e os lábios, sendo os locais comumente envolvidos e, na grande maioria dos casos, são assintomáticos. No caso relatado, a lesão surgiu na mucosa labial inferior após aproximadamente 3 meses de evolução e sua sintomatologia era dolorosa.…”
Section: Discussionunclassified
“…Foi realizada a remoção do tumor, com boa margem de segurança e não houve a necessidade de tratamento radioterápico ou quimioterápico. Há um consenso na literatura afirmando que a exérese cirurgia é o tratamento de escolha, sem necessidade da dissecção cervical, pois raramente esta lesão tem capacidade de causar disseminação ganglionar e seu desenvolvimento é local (ALVAREZ et al, 2014;ROSA et al, 2003;ADORNO et al, 2010;ZANINE et al, 2004;RAHALI et al, 2015;NEVILLE et al, 2016;FRANKLYN et al, 2017).…”
Section: Discussionunclassified
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