Oral Synechia with Epithelial Cyst in Neonate with Cleft Palate: A Case Report

Abstract

Cleft palate with oral synechia is a rare congenital deformity that is represented in the literature by only a handful of cases. Midline synechia is less common than lateral. Failure to recognize and appropriately treat this condition has serious implications for neonatal airway management and feeding. We present a case of cleft palate with midline subglossopalatal synechia that was transferred from an outside institution after a prolonged period of nonsurgical management in which the patient ultimately required intubation for respiratory distress. Release of the synechia was performed without complications. We review the current literature and discuss diagnosis and surgical management of this rare condition.

Subglossopalatal Membrane With Associated Cleft Palate, Cardiovascular, and Neurologic Anomalies

“…Subglossopalatal membrane is a rare congenital oral synechia. It has been described in the literature only a handful of times 1–8 since Nakajima et al 1 first defined it in 1979 (Supplementary Digital Content, Table 1, http://links.lww.com/SCS/D433). Delineation between SGPM and BPM remnants based on embryologic anatomy and associated anomalies have been proposed 2,9 …”

“…It was first described in the literature by Nakajima et al 1 The etiology is unknown, and whereas it has been categorized as a buccopharyngeal membrane (BPM) remnant, Zalzal et al 2 suggests that it may be due to an abnormal fusion event in the 6th or 7th week of gestation. Eight cases in the literature describe subglossopalatal membranes, [1][2][3][4][5][6][7][8] with 5 of them being associated with additional congenital anomalies (Supplementary Digital Content, Table 1, http://links.lww.com/ SCS/D433). Here, we present a case of subglossopalatal membrane with associated anomalies that was treated with surgical excision.…”

Patients With Cleft Lip and Palate Associated With Intraoral Fibrous Bands: A Report of 3 Cases and Review of Literature

“…The epithelial cyst was an uncommon lesion in the oral cavity, especially in a case with intraoral synechia. It possibly occurred due to epithelial trapping during the formation of the synechia (German and Wong, 2011). In our patient, the cyst was removed together with the fibrous bands while the palate repair was performed.…”

Cleft Palate with Lateral Synechiae Syndrome

“…But there have also been reports of cleft palate associated with a single midline synechiae. 4 CPLS can also be associated with hypoplasia of mandible, rarely with hydrocephalus and redundant lower lip tissue. 5 The symptoms are cleft palate, mouth adhesion, inability to fully open mouth and upper airway obstruction.…”