Oral sucrose and non‐nutritive sucking goes some way to reducing pain during retinopathy of prematurity eye examinations

Díllí, Dílek; İlarslan, Nisa Eda Çullas; Kabataş, Emrah Utku; Zencıroğlu, Ayşegül; Şimşek, Yıldız; Okumuş, Nurullah

doi:10.1111/apa.12454

Cited by 40 publications

(58 citation statements)

References 23 publications

(31 reference statements)

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“…Interestingly, in a randomized controlled study aimed to evaluate the efficacy of oral sucrose and non‐nutritive sucking during ROP screening, Dili et al observed significantly lower PIPP scores in the intervention group, but without changes in physiological variables . Similarly, Kabatas et al found a significant effect of oral paracetamol on PIPP scores but not in physiological parameters …”

Section: Discussionmentioning

confidence: 99%

Pain assessment during eye examination for retinopathy of prematurity screening: Skin conductance versus PIPP‐R

et al. 2019

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Aim To assess changes in skin conductance during retinopathy of prematurity screening and to study the correlation between the skin conductance and a validated pain scale. Methods Prospective observational study. Fifty‐three eye examinations were performed in 32 preterm infant candidates for retinopathy of prematurity screening. Outcome measures were changes in Premature Infant Pain Profile‐Revised (PIPP‐R) scale and number of skin conductance fluctuations. Results There was a significant increase from baseline in the number of skin conductance fluctuations and PIPP‐R during the procedure. The maximum value of number of skin conductance fluctuations was 0.64 ± 0.44 peaks/sec, and the maximum value of PIPP‐R was 10.8 ± 3.3. A correlation between the skin conductance and PIPP‐R was not found at any time during the eye examination. Repeated measures correlation analyses showed only a moderate positive correlation between PIPP‐R and number of skin conductance fluctuation values. Conclusion There were significant changes in both PIPP‐R and number of skin conductance fluctuations during retinopathy of prematurity screening, reaffirming that this procedure is painful and stressful. The number of skin conductance fluctuations and PIPP‐R are not significantly correlated, which likely reflects that these parameters evaluate different but complementary aspects of neonatal pain responses.

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Section: Discussionmentioning

confidence: 99%

Pain assessment during eye examination for retinopathy of prematurity screening: Skin conductance versus PIPP‐R

et al. 2019

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“…A total of 9 (7.8 %) infants experienced episodes of desaturations and bradycardia without a significant difference between the groups. Oral paracetamol group had a significantly lower PIPP score during examination of the first eye, following insertion of the speculum [12 (9)(10)(11)(12)(13) vs. 14 (13-15), p 0.01] ( Table 2; Fig. 2).…”

Section: Resultsmentioning

confidence: 99%

“…Therefore many pain-relieving procedures are being tested in ROP examination. Recently, Dilli et al found that oral sucrose has a positive effect in reducing pain during ROP screening [13]. Similarly, Costa et al suggested that oral glucose solution is effective for pain relief during ROP examination [12].…”

Section: Discussionmentioning

confidence: 99%

“…A written consent was obtained from all the parents. This trial According to the results from authors' previous study [13] in a similar group of 32 neonates who underwent ROP screening examination in the NICU, the mean PIPP score was 16.4± 1.8.…”

Section: Methodsmentioning

confidence: 99%

“…Despite topical anesthetics and/or oral administration of non-pharmacological solutions such as oral sucrose, oral glucose or maternal milk before eye examination, most infants score highly on validated pain scores, such as the Premature Infant Pain Profile (PIPP) [11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Efficacy of Single Dose Oral Paracetamol in Reducing Pain During Examination for Retinopathy of Prematurity: A Blinded Randomized Controlled Trial

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Indian J Pediatr

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Effect of Eye Masks on Neonatal Stress Following Dilated Retinal Examination

et al. 2019

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IMPORTANCE Although screening examinations for retinopathy of prematurity (ROP) prevent blindness, they are physiologically stressful for infants. Photosensitivity during mydriasis may contribute to postexamination stress, and reducing light stimulation may make infants more comfortable.OBJECTIVE To determine the effect of a phototherapy mask worn during mydriasis on infant stress in the 12-hour period following ROP screening. DESIGN, SETTING, AND PARTICIPANTSThe Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination (MASK-ROP) randomized clinical trial with patient recruitment from April 2016 to June 2017 at neonatal intensive care units at

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Oral sucrose and non‐nutritive sucking goes some way to reducing pain during retinopathy of prematurity eye examinations

Abstract: Although sucrose combined with non-nutritive sucking modestly reduces pain scores during eye examinations, there is need to further studies to explore significant pain relief for infants undergoing retinopathy of prematurity screening.

Cited by 40 publications

References 23 publications

Pain assessment during eye examination for retinopathy of prematurity screening: Skin conductance versus PIPP‐R

Pain assessment during eye examination for retinopathy of prematurity screening: Skin conductance versus PIPP‐R

Efficacy of Single Dose Oral Paracetamol in Reducing Pain During Examination for Retinopathy of Prematurity: A Blinded Randomized Controlled Trial

Effect of Eye Masks on Neonatal Stress Following Dilated Retinal Examination

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