Oral rehabilitation of a case with regional odontodysplasia using a regenerative approach—A case report and a review of literature

Abstract

Aim to investigate for the first time whether the regenerative approach can be used to rehabilitate a case with regional odontodysplasia (ROD). ROD is a rare, localized developmental anomaly of the dental tissues. Moreover, we review the various treatment protocols for ROD and compare them to the suggested regenerative protocol. Case Report A 22‐year‐old female patient diagnosed with ROD in the upper left quadrant was presented to our clinic. Initially, the affected teeth were extracted and three implants were inserted. A combination of autologous bone marrow mononuclear cells (BMMNCs) seeded on a collagen sponge, nanohydroxyapatite, and autologous platelet‐rich fibrin (PRF) was used to enhance bone regeneration in the defective area and around the inserted implants. After 9 months, bone regeneration and successful osteointegration around the inserted implants were achieved, permitting the insertion of a fourth implant. After an additional six months, a final fixed restoration was constructed. Conclusion The suggested regenerative approach provides a better treatment option for ROD patients to regenerate the lost bone, rehabilitate aesthetics, and restore normal function.

Dental Implants and Plasma Rich in Fibrine: A Wide Literary Review

“…In the scenario of maxillary sinus surgery, the lack of bone in the alveolar ridges has been a major problem in functional aesthetic recovery in patients who have suffered dentoalveolar trauma, traumatic dental extractions, congenital tooth absence, jaw, and mandibular pathologies, in addition to infections due to emotional and the possibility of deformity and also the economic impact they cause on the National Health System (NHS) [1,2].…”

“…It was documented for the first time that the combination of biomaterial and FRP significantly improved bone regeneration in the peri-implant zone. The placement of the implant with the simultaneous use of PRP creates a good relationship between hard and soft tissue, in addition to the advantage of the psychological relationship with the patient [1].…”

“…Implantology stands out as a modern method of oral rehabilitation for total or partially edentulous patients. For this method to develop properly, bone integration of the implant into the recipient bone tissue is necessary, since bone integration is the key to clinical surgical success, which will be completed after the prosthetic phase is over [1].…”

“…The maxillary sinus is the largest of the paranasal sinuses and has the function of contributing to the resonance of phonation, conditioning of the air we breathe and aid in the production of mucus in the nasal cavity [1]. It also acts to equalize barometric pressures in the nasal cavity, which is covered by a membrane called the Schneider membrane.…”

“…The importance of knowing the constitution of this epithelium is because these hair cells play a fundamental role in the physiology of the maxillary sinus. While the calciform cells produce mucus, these cilia generate movements that cause this mucus to move to the drainage site of the maxillary sinus [1].…”