Oral pyogenic granuloma presenting as an atypically large soft tissue mass: A case report

Limmonthol, Saowaluck; Sayungkul, Chakkrit; Klanrit, Poramate

doi:10.1016/j.ajoms.2012.12.012

Cited by 5 publications

(5 citation statements)

References 16 publications

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“…En el caso presentado, se trataba de lesiones exofiticas, color violáceo, según la clasificación se encontrarían en la segunda fase. El GP se presenta en cavidad oral, pero también se muestra en nasofaringe (18), el intestino delgado, colon, recto, cicatrices de quemaduras (19), además se ha reportado en lechos ungueales de dedos de manos y pie (14).…”

Section: Discussionunclassified

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An unusual case of multiple oral pyogenic granuloma, ¿associated with treatment with levothyroxin?

Patiño-Paul¹

2021

Rev Estomatol Herediana.

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El Granuloma piógeno (GP) es una lesión tumoral, no neoplásica, vascular, generalmente solitaria, que se presenta en la cavidad oral o piel, la etiología aún no está muy clara, se considera que es una lesión reactiva a varios estímulos de bajo grado, entre los cuales podemos contar traumas repetidos, agresiones, factores hormonales y ciertos fármacos. El GP múltiple, es un fenómeno raro, generalmente asociado al uso de drogas, como la carbamacepina, ciclosporina, retinoides, levotiroxina, etc. Se presenta el caso de una paciente de 50 años, referida por presentar aumento de volumen en reborde alveolar del primer, tercer y cuarto cuadrantes; con antecedentes de psoriasis eritrodermica e hipotiroidismo, en tratamiento con levotiroxina aproximadamente seis meses antes que se presenten las lesiones; se realiza exeresis quirúrgica y curetaje subperiostico, se enviaron las muestras a anatomía patológica, confirmándose el diagnóstico definitivo de GP; por los antecedentes, y la aparición casi simultánea de las lesiones en múltiples cuadrantes, se sospecha que estas, están asociadas al consumo terapéutico de levotiroxina para el hipotiroidismo.

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Section: Discussionunclassified

“…De los tres GP reportados, el del maxilar superior medía más de 2.5 cm, la literatura considera a estos GP como "gigantes" (9,15); y se sugirió que algunos casos están relacionados con pacientes sistémicamente comprometidos, aunque se encontraron publicaciones de GP gigantes en pacientes sanos, incluido gestantes (19).…”

Section: Discussionunclassified

An unusual case of multiple oral pyogenic granuloma, ¿associated with treatment with levothyroxin?

Patiño-Paul¹

2021

Rev Estomatol Herediana.

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“…Angiogenesis is a crucial step in the pathogenesis of PG and the development of PG is dependent on the deregulation in the balance between angiogenic and anti-angiogenic effects. [ 7 ]…”

Section: Discussionmentioning

confidence: 99%

Simultaneous occurrence of pyogenic granuloma at multiple sites associated with bone loss: Report of a rare case

Mohanty

Satpathy

2018

J Indian Soc Periodontol

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Pyogenic granuloma (PG) is a reactive hyperplasia of connective tissue that occurs in response to low-grade local irritation, traumatic injury, foreign materials, or hormonal causes and rarely associated with bone loss. Although solitary PG is a common lesion in the orofacial region, presence of multiple such lesions at the same time with associated bone loss is rare. In addition, repeated recurrences of such lesions sometimes frustrate the clinician. This article presents a rare case of simultaneous occurrence of PG at multiple sites associated with bone loss in a young female and its management.

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“…[ 3 ] At present, there are two different histological types of PG namely lobular capillary hemangioma (LCH) type and non-LCH type. [ 4 5 6 ]…”

Section: Introductionmentioning

confidence: 99%

Idiopathic huge pyogenic granuloma in young and old: An unusually large lesion in two cases

Punde

Malik

et al. 2013

J Oral Maxillofac Pathol

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Pyogenic granuloma (PG) is a reactive hyperplasia of connective tissue in response to local irritants, chronic irritation and hormonal changes. It is a tumor-like growth of the oral cavity frequently located in the region surrounding the anterior teeth or skin. It usually arises in response to various stimuli, such as low-grade local irritation, traumatic injury, hormonal factors or certain kinds of drugs. Clinically, the lesion appears as a smooth, lobulated, exophytic mass, exhibiting pink to reddish-purple color which can bleed on slight manipulation. PG has no malignant potential, but recurrence is common after surgical excision. Histologically, the surface epithelium may be intact and may show foci of ulcerations or exhibit hyperkeratosis. Gingiva is the most common site affected followed by buccal mucosa, tongue and lips. The size of lesion varies from millimeters to several centimeters; rarely exceeding 2-2.5 cm. PG larger than 2.5 cm are seldom reported. Estrogen has been considered as a major contributing factor in most of the cases. Thus, occurrence of PG is mostly seen in premenopausal age due to high levels of estrogen. In this article, two unusually large oral PG have been reported. In the first case, a 25-year-old young male patient and in the second case, 70-year-old female patient have been described. In both the cases, the size of lesion was more than 5 cm which has been rarely reported before. Also one of the cases describe here is of a postmenopausal female, which questions role of estrogen as an etiological factor.

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Oral pyogenic granuloma presenting as an atypically large soft tissue mass: A case report

Cited by 5 publications

References 16 publications

An unusual case of multiple oral pyogenic granuloma, ¿associated with treatment with levothyroxin?

An unusual case of multiple oral pyogenic granuloma, ¿associated with treatment with levothyroxin?

Simultaneous occurrence of pyogenic granuloma at multiple sites associated with bone loss: Report of a rare case

Idiopathic huge pyogenic granuloma in young and old: An unusually large lesion in two cases

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