Oral promethazine hydrochloride in ethylenediamine‐sensitive patients

Abstract

A study of 12 patients with allergic contact sensitivity to ethylenediamine has shown that exposure to the oral antihistamine promethazine hydrochloride (Phenergan) did not result in an exacerbation or recrudescence of eczema. This would suggest that promethazine may be safely administered to ethylenediamine-sensitive patients contrary to advice given in some of the dermatological literature.