Oral mucosa lesions in COVID‐19

Petrescu, Nausica Bianca; Lucaciu, Ondine; Roman, Alexandra

doi:10.1111/odi.13499

Cited by 40 publications

(58 citation statements)

References 9 publications

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“…Lymphocytopenia and T-cell over-activation with reduction of an effective humoral / cellular immune response have been reported in COVID-19 patients( Dziedzic and Wojtyczka, 2020 , Xu et al, 2020 ). Dysfunctions such as anosmia and ageusia have been found as inflammation-induced symptoms of COVID-19( Petrescu et al 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Oral manifestations in a patient with a history of asymptomatic COVID-19: Case report

Ojeda¹,

Ulloa²

2020

International Journal of Infectious Diseases

104

139

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Highlights Lesions in the oral mucosa in patients with suspected or confirmed SARS-CoV-2 infection can be detected and monitored. Teleconsultation facilitates the interdisciplinary approach (doctor-dentist). Clinical findings: Candida albicans (opportunistic lesion), thrush, petechiae (oral and facial mucosa), melanin hyperpigmentation at the gingival level. Antifungal treatment results are presented.

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Section: Introductionmentioning

confidence: 99%

Oral manifestations in a patient with a history of asymptomatic COVID-19: Case report

Ojeda¹,

Ulloa²

2020

International Journal of Infectious Diseases

104

139

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“…[34][35][36] In addition, several case reports have reported oral ulcers, petechiae, and reddish macules particularly in the palate. [37][38][39][40][41][42] Other areas include tongue, lips, and the buccal mucosa. 37 Fissured lips and strawberry tongue are a presentation of the multisystem inflammatory syndrome in children positive for SARS-CoV-2 antibodies.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Pandemic: Oral Health Challenges and Recommendations

et al. 2020

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The aim of this article is to shed light on coronavirus disease 2019 (COVID-19) and its oral effects and risk of nosocomial transmission to update the knowledge of dental health care workers. A thorough literature search of the PubMed/Embase/Web of Science/Cochrane central database was conducted to identify the impact of COVID-19 on oral health. We reviewed the recommendations on the recent guidelines set by the Centers for Disease Control and Prevention infection control practices for dentistry, American Dental Association, and the World Health Organization. According to the available evidence, COVID-19 may have a negative impact on the oral health due to the infection itself and due to various other consequences such as therapeutic measures, xerostomia, and other complications of the COVID-19. In light of the above facts, dentists should be wary of the disease, its identification, mode of spread and impacts on the oral health. The dental personnel have been identified as at the highest risk of getting COVID-19 due to cross infection from contact with their patients and aerosols generated in routine dental procedures. As such, they should be aware of the modifications that need to be made to the practice to prevent transmission of the disease. It is evident that COVID-19 has a negative impact on the oral health and at the same time a significant transmission risk to the dental personnel and patients who visit the clinic. If the recommendations issued by the regulatory authorities are meticulously followed, the risk of disease transmission can be lessened.

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“…In the case reported by Chaux-Bodard et al [ 6 ], vascular inflammation related to SARS-CoV-2 was proposed to be responsible for the macular erythematous lesion found in their patient. In corroboration, inflammation-induced loss of taste and smell were pointed out to be confirmed symptoms of the disease [ 31 ]. Oral ulcerations were reported as an early symptom in 9 patients with pediatric multisystem inflammatory syndrome associated with COVID-19 [ 22 ].…”

Section: Discussionmentioning

confidence: 89%

“…Since the mouth is one of the first sites that come into contact with SARS-CoV-2, it has been hypothesized that oral mucosal lesions may be the first sign of COVID-19 [ 31 ], especially considering the multiorgan involvement of the disease. Lack of oropharyngeal examination may explain the paucity of reports on oral manifestations of COVID-19 [ 20 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

Is SARS-CoV-2 an Etiologic Agent or Predisposing Factor for Oral Lesions in COVID-19 Patients? A Concise Review of Reported Cases in the Literature

Etemad‐Moghadam

Alaeddini

2021

International Journal of Dentistry

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The pathogenic mechanism of SARS-CoV-2 infection is unclear, and its symptoms vary in different patients. Initial reports of COVID-19 concentrated on pulmonary issues, but with time, additional features such as hyposmia/anosmia, dysgeusia, and skin lesions were added to the list of COVID-19 symptoms. There have been an increasing number of reports on oral cavity lesions in individuals with COVID-19, which might be relevant considering that this location is one of the first sites coming into contact with the virus and that it contains the SARS-CoV-2 receptor. We hereby aim to familiarize practicing head and neck clinicians with the range of oral lesions reported in COVID-19 patients and to critically appraise the most recent data on the role of SARS-CoV-2 in these lesions. We also discuss the ongoing debate on the direct/indirect association of oral symptoms with the disease. COVID-19 cases with simultaneous oral symptoms were extracted from the literature, and articles discussing the role of SARS-CoV-2 in oral lesions were compiled and methodically analyzed. We found approximately 95 COVID-19 patients with a wide range of oral lesions. Based on current evidence, the exact role of SARS-CoV-2 in the development of oral lesions remains unclear. Oral examination of patients is needed to provide adequate cases for analysis to clarify unknown problems related to COVID-19. There is evidence to support both the direct and indirect roles of SARS-CoV-2 in the development of oral lesions. Awareness of the possibility of oral manifestations in COVID-19 is important to clarify the range of disease signs and symptoms.

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Oral mucosa lesions in COVID‐19

Cited by 40 publications

References 9 publications

Oral manifestations in a patient with a history of asymptomatic COVID-19: Case report

Oral manifestations in a patient with a history of asymptomatic COVID-19: Case report

COVID-19 Pandemic: Oral Health Challenges and Recommendations

Is SARS-CoV-2 an Etiologic Agent or Predisposing Factor for Oral Lesions in COVID-19 Patients? A Concise Review of Reported Cases in the Literature

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