Oral manifestations of sarcoidosis: Report of a case masquerading as a neoplasm

DeLuke, Dean M.; Sciubba, James J.

doi:10.1016/0030-4220(85)90015-5

Cited by 22 publications

(5 citation statements)

References 13 publications

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“…16 The literature is unclear as to treatment of oral lesions diagnosed as sarcoidosis. Some authors report healing with only surgical excision of the lesion, others 8,17,18 report healing with only medical treatment, whereas others [19][20][21] describe amelioration by combining medical and surgical treatment. Hoggins and Allan 9 report cases treated by irradiation, and others 8,22,23 describe spontaneous healing or stabilization.…”

Section: Discussionmentioning

confidence: 99%

Upper respiratory tract involvement of sarcoidosis in the Turkish population

Yanardağ

Enöz²,

Papila

et al. 2006

Otolaryngol.--head neck surg.

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Section: Discussionmentioning

confidence: 99%

Upper respiratory tract involvement of sarcoidosis in the Turkish population

Yanardağ

Enöz²,

Papila

et al. 2006

Otolaryngol.--head neck surg.

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“…Although the lung is the primary site of involvement in most cases, the involvement of head and neck sites is well documented. Several case reports of sarcoidosis masquerading as head and neck malignancies exist 1 , 2 . Isolated tonsillar involvement is rare but has been documented 3 …”

Section: Discussionmentioning

confidence: 99%

A noncaseating granulomatous lesion of the tonsil presenting as a malignant neoplasm

Yueh

Woods

Koch

1995

Otolaryngol.--head neck surg.

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Illoncaseating granulomatous lesions of the tonsil are uncommon. Arriving at a specific diagnosis depends on the clinical history, characteristic histologic appearance, and supportive laboratory, radiologic, and skin testing. Sarcoidosis is a chronic multisystem disease characterized by noncaseatmg granuloma formation. It has been reported to involve the tonsil and should be considered in the differential of tonsillar masses. Exclusion of tubercular, fungal, and neoplastic processes is critical. We present a patient in whom sarcoid involvement of the tonsil initially m a s q u e r a d e d as a malignancy. CASE REPORTA 78-year-old black man was referred to the otolaryngology clinic with a several-week history of throat pain and a left neck mass unresponsive to antibiotics. The patient also reported weight loss and severe dysphagia. He had no history of alcohol or tobacco use, and his past medical history was unremarkable. Examination revealed prominent left tonsillar fullness accompanied by a nontender, firm, 6-cm left jugulodigastric node. The white blood cell count was 2.4 thousand cells/mmL The remainder of his hematology and chemistry panels were normal, including calcium and liver function test results. Chest x ray was normal.A computed tomogram was obtained and reveated a large submucosal, infiltrative mass in the tonsil extending inferiorly to the supraglottic region, with massive cervical adenopathy (Fig. 1). Fine-needle aspiration biopsy specimens of the left neck mass were nondiagnostic. A panendoscopy was performed, which confirmed the presence of

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“…The first case of sarcoidosis with the involvement of oral lesion was reported by Schroff in 1942. [ 2 ] This disease most commonly affects the respiratory system with approximately 90% of patients presenting pulmonary manifestation, 25% cutaneous, and 10–15% with head and neck manifestations. [ 3 ] Oral involvement of this disease is relatively rare and mostly affects buccal mucosa, lips, gingiva, tongue, and palate.…”

Section: Introductionmentioning

confidence: 99%

Sarcoidosis: Oral and extra-oral manifestation

Gupta¹,

Tripathi²,

Kumar³

et al. 2015

J Indian Soc Periodontol

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Sarcoidosis is a multisystem granulomatous disease, which is usually associated with the formation of noncaseating granulomas in affected tissues and organs. It is mostly present with bilateral hilar lymphadenopathy, pulmonary infiltration, ocular, and cutaneous lesions. Oral manifestations of this disease are relatively rare. The present case report shows a 40-year-old male with lesions in the soft tissue of oral cavity (buccal mucosa, gingiva, and palate) and a diagnosis of sarcoidosis was established following hematological, biochemical and pulmonary function tests, chest radiograph, and histopathological investigation.

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Oral manifestations of sarcoidosis: Report of a case masquerading as a neoplasm

Cited by 22 publications

References 13 publications

Upper respiratory tract involvement of sarcoidosis in the Turkish population

Upper respiratory tract involvement of sarcoidosis in the Turkish population

A noncaseating granulomatous lesion of the tonsil presenting as a malignant neoplasm

Sarcoidosis: Oral and extra-oral manifestation

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